Journals / Acta Orthopaedica et Traumatologica Turcica / 2026 / Cilt: 30 Sayı: 1

The results of fresh osteochondral autograft and allografts utilized in osteochondral defects

Osteokondral defektlerde uygulanan taze osteokondral otogreft ve allogrefet sonuçları

Pages
67–72
Publication Date
2006-09-11
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Upon assessment it was thought that there were more degenerative changes in fresh osteochondral allografts compared with autografts and that this may be due to depression in allografts and immunologic response.

📌 3 Key Takeaways

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Objective & Hypothesis:To investigate the results of fresh osteochondral autografts and allografts applied in joint cartilage losses, 70 guinea pigs were studied.
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Key Findings & Data:In our study in which 10 guinea pigs were used as control group, osteochondral defects were formed in the right knees of the animals.
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Conclusion & Impact:Upon assessment it was thought that there were more degenerative changes in fresh osteochondral allografts compared with autografts and that this may be due to depression in allografts and immunologic response.
🔬Design:Makale
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

To investigate the results of fresh osteochondral autografts and allografts applied in joint cartilage losses, 70 guinea pigs were studied. In our study in which 10 guinea pigs were used as control group, osteochondral defects were formed in the right knees of the animals. These defects were restored by fresh osteochondral autografts and allografts. In the first, third and sixth weeks, the macroscopic histologic and histochemical evaluations of the grafts were made. Upon assessment it was thought that there were more degenerative changes in fresh osteochondral allografts compared with autografts and that this may be due to depression in allografts and immunologic response.

Özet

Eklem kıkırdak kayıplarında uygulanan taze osteokondral otogreft ve allogreftlerin sonuçlarını araştırmak için 70 kobay üzerinde çalışıldı. 10 kobayın kontrol grubu olarak kullanıldığı çalışmamızda, kobayların sağ dizlerinde osteokondral defektler oluşturuldu. Bu defektler taze osteokondral otogretler ve allogreftler ile onarılarak 1, 3. ve 6. haftalarda greftler makroskopik, histolojik olarak değerlendirildi. Yapılan değerlendirmede, taze osteokondral allogreftlerde otogreftlere göre daha fazla dejeneratif değişiklikler olduğu, bunun allogreftlerde oluşan çökme ve immünolojik yanıta bağlı olduğu düşünüldü.

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Cite This Article

Hasturk, A., Bilgen, O., Durak, K., Aydinli, U. (2006). The results of fresh osteochondral autograft and allografts utilized in osteochondral defects. Acta Orthopaedica et Traumatologica Turcica, Cilt: 30 Sayı: 1, 67–72. https://doi.org/10.3944/aott.v30i1.4153

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