Journals / Akademik Gastroenteroloji Dergisi / 2026 / Cilt: 2 Sayı: 2

Prevalence of spontaneous ascites infection in patients with cirrhosis and its risk factors

Sirozlu hastalarda spontan assit enfeksiyonunun görülme oranı ve risk faktörleri

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Publication Date
2003-08-01
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⚡ TL;DR(Too Long; Didn't Read)

The rates of patients with ascitic fluid total protein lower than 1 g/dl, previous spontaneous ascites infection and previous gastrointestinal hemorrhage were significantly higher than those of patients with sterile ascites (p

📌 3 Key Takeaways

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Objective & Hypothesis:Background and aim: It has been suggested that several factors influence the development and prevalence of spontaneous ascites infection in cirrhosis.
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Key Findings & Data:Material and methods: 68 patients (20 female and 48 male, mean age 48.76 ± 7.49) with cirrhosis and ascites due to various etiologies (30 HBV, 14 HCV, 16 alcohol, 8 cryptogenic) were evaluated after hospitalization.
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Conclusion & Impact:The rates of patients with ascitic fluid total protein lower than 1 g/dl, previous spontaneous ascites infection and previous gastrointestinal hemorrhage were significantly higher than those of patients with sterile ascites (p
🔬Design:Makale
📍Scope:Comprehensive Sample
⚙️Variables:Siroz · spontan assit enfeksiyonu · Cirrhosis

Abstract

Background and aim: It has been suggested that several factors influence the development and prevalence of spontaneous ascites infection in cirrhosis. The aim of this prospective study was to define the prevalence of spontaneous ascites infection (SAI) and its risk factors in our cirrhotic patient population. Material and methods: 68 patients (20 female and 48 male, mean age 48.76 ± 7.49) with cirrhosis and ascites due to various etiologies (30 HBV, 14 HCV, 16 alcohol, 8 cryptogenic) were evaluated after hospitalization. Inoculation of samples from ascites fluid into the hemoculture bottles and spreading onto lames for Gram staining was done at the bedside, as well as measurement of several biochemical parameters in serum and ascitic fluid. Results: SAI was defined in 14 (20.58 %) of the patients. Out of these cases, 7 were culture negative neutrocytic ascites, 6 spontaneous bacterial peritonitis and 1 monobacterial non-neutrocytic ascites. Out of these patients, 8 (57.14 %) were in C stage, and 6 (42.85 %) in B stage according to Child-Pugh classification. HBV was the etiologic factor in 8 (57.14 %), HCV in 2 (14.28 %) and alcohol in 4 (28.57 %) patients. We found on difference among the etiologic groups and Child-Pugh groups in view of the development of SAI. The rates of patients with ascitic fluid total protein lower than 1 g/dl, previous spontaneous ascites infection and previous gastrointestinal hemorrhage were significantly higher than those of patients with sterile ascites (p

Özet

Giriş ve amaç: Sirozda spontan assit enfeksiyonu gelişmesini ve prevalansı nı etkileyen bir takım faktörler ileri sürülmektedir. Bu prospektif çalışmanın amacı, sirotik hasta grubumuzda spontan assit enfeksiyonu prevalansını ve risk faktörlerini belirlemekti. Gereç ve yöntem: Farklı nedenlere bağlı (30 HBV, 14 HCV, 16 alkol, 8 kriptojenik) sirozu olan assitli 68 hasta (20 kadın ve 48 erkek, ortalama yaş 48.76 ± 7.49) hastaneye yatırılarak incelendi. Serum ve assit sıvısında bir takım biyokimyasal parametreler incelenirken, assit sıvısı örneklerinin hemokültür şişelerine konması ve gram boyaması için lama yayılması hasta başında gerçekleştirildi. Bulgular: 14 hastada (% 20.58) spontan assit enfeksiyonu saptandı. Bu vakaların 7'si kültür negatif nötrositik assit, 6'sı spontan bakteriyel peritonit ve 1'i monobakteriyel nonnötrositik assit idi. Child- Pugh sınıflamasına göre 8 hasta (% 57.14) C evresinde, 6 hasta (% 42.85) B evresinde idi. 8 hastada (% 57.14) HBV, 2 hastada (% 14.28) HCV ve 4'ünde (% 28.57) alkol etyolojik faktördü. Spontan assit enfeksiyonu gelişiminde, Child-Pugh sınıflaması ve etyolojik gruplara göre fark yoktu. Steril assiti olan hastalara göre assit sıvısı total protein düzeyi 1 g/dL'nin altında olması, geçirilmiş spontan assit enfeksiyonu ve geçirilmiş gastrointestinal kanama görülme oranı anlamlı olarak daha yüksekti (p

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Cite This Article

Bağcı, S., Ayta, H., Tüzün, A., Ateş, Y., Erçin, N., Uygun, A., Gülşen, M., Karaeren, N., Dağalp, K. (2003). Prevalence of spontaneous ascites infection in patients with cirrhosis and its risk factors. Akademik Gastroenteroloji Dergisi, Cilt: 2 Sayı: 2. https://ajindex.com/articles/1187874

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