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Journals / Akademik Gastroenteroloji Dergisi / 2021 / Cilt: 20 Sayı: 2

Kaposi sarcoma development after azathioprine use in a patient with autoimmune hepatitis: A case report

Otoimmün hepatit tanılı hastada azatioprin tedavisi sonrası gelişen Kaposi sarkomu

Tuğçe Çağlar(Gazi Üniversitesi Tıp Fakültesi, İç Hastalıkları Anabilim Dalı, Ankara)0000-0003-0950-0530
Azar Abiyev(Gazi Üniversitesi Tıp Fakültesi, Gastroenteroloji Bilim Dalı, Ankara)0000-0002-9840-7348
Özlem Erdem(Gazi Üniversitesi Tıp Fakültesi, Patoloji Anabilim Dalı, Ankara)0000-0002-5981-4856
Murat Kekilli(Gazi Üniversitesi Tıp Fakültesi, Gastroenteroloji Bilim Dalı, Ankara)0000-0002-3063-8748
İbrahim Doğan(Gazi Üniversitesi Tıp Fakültesi, Gastroenteroloji Bilim Dalı, Ankara)0000-0002-5859-1806
Pages
123–126
Publication Date
2021-08-26
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

We present an human immmunodeficiency virus-negative case who received azathioprine treatment for autoimmune hepatitis and subsequently developed Kaposi sarcoma.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Kaposi sarcoma is a mesenchymal neoplasm associated with human herpes virus-8.
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Key Findings & Data:It is usually found in patients who have primary or secondary immune deficiency.
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Conclusion & Impact:We present an human immmunodeficiency virus-negative case who received azathioprine treatment for autoimmune hepatitis and subsequently developed Kaposi sarcoma.
🔬Design:Olgu Sunumu
📍Scope:Comprehensive Sample
⚙️Variables:Otoimmün hepatit · azatioprin · Kaposi sarkomu

Abstract

Kaposi sarcoma is a mesenchymal neoplasm associated with human herpes virus-8. It is usually found in patients who have primary or secondary immune deficiency. Immunomodulatory drugs such as azathioprine are effective in the treatment of autoimmune hepatitis. However, their use is limited due to toxicity concerns. We present an human immmunodeficiency virus-negative case who received azathioprine treatment for autoimmune hepatitis and subsequently developed Kaposi sarcoma.

Özet

Kaposi sarkomu, insan herpes virüsü-8 ile ilişkili mezenkimal bir neoplazmdır. Genellikle birincil veya ikincil immün yetmezliği olan hastalarda bulunur. Azatioprin gibi immünomodülatör ilaçlar otoimmün hepatit hastalığında etkilidir, ancak bunların kullanımı toksisite endişeleri nedeniyle sınırlıdır. Burada, otoimmün hepatit hastalığı için azatioprin tedavisi alan ve sonrasında Kaposi sarkomu gelişen, insan immün yetmezlik virüsü negatif bir olguyu sunuyoruz.

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Cite This Article

Çağlar, T., Abiyev, A., Erdem, Ö., Kekilli, M., Doğan, İ. (2021). Kaposi sarcoma development after azathioprine use in a patient with autoimmune hepatitis: A case report. Akademik Gastroenteroloji Dergisi, Cilt: 20 Sayı: 2, 123–126. https://doi.org/10.17941/agd.978336

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