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Journals / Akademik Gastroenteroloji Dergisi / 2023 / Cilt: 22 Sayı: 3

Perioperative Findings and Postoperative Complications in Living Donor Liver Transplantation Recipients with High MELD Scores

MELD Skoru Yüksek Canlı Vericili Karaciğer Nakli Alıcılarında Perioperatif Bulgular ve Postoperatif Komplikasyonlar

Ender Anılır(İstanbul Aydın University Medicalpark Florya Hospital, Organ Transplantation Center)0000-0002-0024-1790
Feyza Sönmez Topcu(İstanbul Aydın University Medikalpark Florya Hospital, Radiology Department)0000-0002-7450-2949
Alihan Oral(Fenerbahce University, Medicana Hospital İnternal Medicine Department)0000-0003-1160-9340
Emrah Şahin(İstanbul Aydın University Medikalpark Florya Hospital, Organ Transplantation Center)0000-0001-5267-9068
Abuzer Dirican(İstanbul Aydın University Medikalpark Florya Hospital, Organ Transplantation Center)0000-0002-8647-3268
Bülent Ünal(İstanbul Aydın University Medikalpark Florya Hospital, Organ Transplantation Center)0000-0003-2538-7961
Pages
150–154
Publication Date
2023-12-22
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The MELD score must be taken into consideration when preparing the patient and making a treatment plan.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Background and Aims: We aimed to investigate the effect of the high MELD score on perioperative recipient/graft ischemia times and postoperative complications.
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Key Findings & Data:The patients were grouped and examined according to their MELD score under and above 20.
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Conclusion & Impact:The MELD score must be taken into consideration when preparing the patient and making a treatment plan.
🔬Design:Araştırma Makalesi
📍Scope:Comprehensive Sample
⚙️Variables:MELD · karaciğer · nakil

Abstract

Background and Aims: We aimed to investigate the effect of the high MELD score on perioperative recipient/graft ischemia times and postoperative complications. Materials and Method: One hundred and seventy-two patients who underwent living-donor liver transplantation for end stage liver cirrhosis were included in the study. The patients were grouped and examined according to their MELD score under and above 20. Anhepatic phase, cold ischemia time, operation time, blood product transfusion, total hospital and intensive care unit staying time rates, biliary complications, hepatic vein thrombosis, portal vein thrombosis, postoperative hemorrhage, sepsis, and primary graft dysfunction were analyzed statistically. Results: Cold ischemia time (p = 0.046) was statistically longer in patients with MELD >20. A result very close to the statistically significant P value regarding perioperative blood transfusion was obtained. Conclusion: Cold ischemia time increases with increasing MELD. The MELD score must be taken into consideration when preparing the patient and making a treatment plan.

Özet

Giriş ve Amaç: Yüksek MELD skorunun perioperatif alıcı/greft iskemi süreleri ve postoperatif komplikasyonlar üzerine etkisini araştırmayı amaçladık. Gereç ve Yöntem: Çalışmaya, son dönem karaciğer sirozu nedeniyle canlı vericiden karaciğer nakli yapılan 172 hasta dahil edildi. Hastalar MELD skorları 20'nin altında ve üstünde olanlara göre gruplandırılarak incelendi. Anhepatik faz, soğuk iskemi süresi, operasyon süresi, kan ürünü transfüzyonu, toplam hastane ve yoğun bakım ünitesinde kalış süresi, safra komplikasyonları, hepatik ven trombozu, portal ven trombozu, postoperatif kanama, sepsis ve primer greft disfonksiyonu istatistiksel olarak analiz edildi. Bulgular: MELD >20 olan hastalarda soğuk iskemi süresi (p = 0,046) istatistiksel olarak daha uzundu. Perioperatif kan transfüzyonuna ilişkin istatistiksel olarak anlamlı P değerine çok yakın bir sonuç elde edildi. Sonuç: MELD arttıkça soğuk iskemi süresi de artmaktadır. Hasta hazırlanırken ve tedavi planı yapılırken MELD skoru dikkate alınmalıdır.

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Cite This Article

Anılır, E., Topcu, F. S., Oral, A., Şahin, E., Dirican, A., Ünal, B. (2023). Perioperative Findings and Postoperative Complications in Living Donor Liver Transplantation Recipients with High MELD Scores. Akademik Gastroenteroloji Dergisi, Cilt: 22 Sayı: 3, 150–154. https://doi.org/10.17941/agd.1405010

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