Journals / Cukurova Medical Journal / 2019 / Cilt: 44 - Sayı: 2

Effects of dietary high fructose and saturated fatty acids on chronic low grade inflammation in the perspective of chronic diseases

Kronik hastalıklar ekseninde diyette yüksek fruktoz ve doymuş yağ asitlerinin kronik düşük derece inflamasyon üzerine etkisi

Pages
685–694
Publication Date
2019-06-30
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In this review, the effects of dietary high fructose and saturated fatty acids on development of chronic low grade inflammation through some proinflammatory mediators were examined.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:In recent years, the role of chronic low grade inflammation in the emergence of chronic diseases has been emphasized.
📊
Key Findings & Data:Chronic low grade inflammation is a metabolic process characterized by systemic circulation and increased inflammatory mediators and some proinflammatory cytokines in various tissues.
💡
Conclusion & Impact:In this review, the effects of dietary high fructose and saturated fatty acids on development of chronic low grade inflammation through some proinflammatory mediators were examined.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:saturated fatty acid · fructose · inflammation

Abstract

In recent years, the role of chronic low grade inflammation in the emergence of chronic diseases has been emphasized. Chronic low grade inflammation is a metabolic process characterized by systemic circulation and increased inflammatory mediators and some proinflammatory cytokines in various tissues. C-reactive protein (CRP), tumor necrosis factor-α (TNF-α), interleukin-1 (IL-1), interleukin-4 (IL-4), interleukin-6 (IL-6), toll like receptor-4 (TLR-4) are some proinflammatory molecules that play a role in the chronic low grade inflammation. Recent studies have shown that fructose and saturated fatty acids, which are consumed with increased consumption of processed foods in the current diet, might trigger chronic low grade inflammation. In this review, the effects of dietary high fructose and saturated fatty acids on development of chronic low grade inflammation through some proinflammatory mediators were examined.

Özet

Son yıllarda kronik hastalıkların ortaya çıkmasında, kronik düşük derece inflamasyonun rolü üzerinde durulmaktadır. Kronik düşük derece inflamasyon, sistemik dolaşım ve çeşitli dokularda inflamatuvar medyatörlerin ve bazı proinflamatuvar sitokinlerin artışı ile karakterize olan metabolik bir süreçtir. C reaktif protein (CRP), tümör nekrozis faktör-α (TNF-α), interlökin-1 (IL-1), interlökin-4 (IL-4), interlökin-6 (IL-6), toll benzeri reseptör-4 (TLR-4) kronik düşük derece inflamasyonda rol oynayan bazı proinflamatuvar moleküllerdir. Güncel çalışmalarda, hazır ve işlenmiş besinlerin tüketimiyle artan fruktoz ve doymuş yağ asitleri alımının kronik düşük derece inflamasyon oluşumunda etkileri olduğu gösterilmektedir. Bu derlemede, diyetle yüksek fruktoz ve doymuş yağ asitleri alımının, proinflamatuvar medyatörler aracılığıyla kronik düşük derece inflamasyon oluşumuna etkisi incelenmiştir.

🔖

Cite This Article

BODUR, M., ÜNAL, R. N. (2019). Effects of dietary high fructose and saturated fatty acids on chronic low grade inflammation in the perspective of chronic diseases. Cukurova Medical Journal, Cilt: 44 - Sayı: 2, 685–694. https://ajindex.com/articles/116929

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (14)

  1. World Health Organization. Global status report on noncommunicable diseases 2010. Geneva, WHO, 2010
  2. Velickovic N, Teofilovic A, Ilic D, Djordjevic A, Vojnovic Milutinovic D, Petrovic S et al. Modulation of hepatic inflammation and energy-sensing pathways in the rat liver by high-fructose diet and chronic stress. Eur J Nutr. 2018
  3. Zaki SM, Abdel Fattah S, Hassan DS. The differential effects of high-fat and high fructose diets on the liver of male albino rat and the proposed underlying mechanisms. Folia Morphol (Warsz). 2018
  4. Zitvogel L, Pietrocola F, Kroemer G. Nutrition, inflammation and cancer. Nat Immunol. 2017;18:843- 50
  5. Silveira BKS, Oliveira TMS, Andrade PA, Hermsdorff HHM, Rosa COB, Franceschini S. Dietary pattern and macronutrients profile on the variation of inflammatory biomarkers: scientific update. Cardiol Res Pract. 2018;2018:4762575
  6. Calder PC, Ahluwalia N, Albers R, Bosco N, BourdetSicard R, Haller D, et al. A consideration of biomarkers to be used for evaluation of inflammation in human nutritional studies. Br J Nutr. 2013;109l 1:S1-34
  7. Barbaresko J, Koch M, Schulze MB, Nothlings U. Dietary pattern analysis and biomarkers of low-grade inflammation: a systematic literature review. Nutr Rev. 2013;71(8):511-27
  8. Zhang DM, Jiao RQ, Kong LD. High dietary fructose: direct or indirect dangerous factors disturbing tissue and organ functions. Nutrients. 2017;9(4)
  9. Nishida K, Otsu K. Inflammation and metabolic cardiomyopathy. Cardiovasc Res. 2017;113(4):389-98
  10. Kuzma JN, Cromer G, Hagman DK, Breymeyer KL, Roth CL, Foster-Schubert KE, et al. No differential effect of beverages sweetened with fructose, highfructose corn syrup, or glucose on systemic or adipose tissue inflammation in normal-weight to obese adults: a randomized controlled trial. Am J Clin Nutr. 2016;104(2):306-14
  11. Ruiz-Nunez B, Dijck-Brouwer DA, Muskiet FA. The relation of saturated fatty acids with low-grade inflammation and cardiovascular disease. J Nutr Biochem. 2016;36:1-20
  12. DiNicolantonio JJ, Lucan SC, O'Keefe JH. The evidence for saturated fat and for sugar related to coronary heart disease. Prog Cardiovasc Dis. 2016;58:464-72
  13. Ekici M, Kisa U, Arikan Durmaz S, Ugur E, NergizUnal R. Fatty acid transport receptor soluble CD36 and dietary fatty acid pattern in type 2 diabetic patients: a comparative study. Br J Nutr. 2018;119(2):153-62
  14. Calder PC, Ahluwalia N, Brouns F, Buetler T, Clement K, Cunningham K et al. Dietary factors and low-gr