SavedAdd your journal

Journals / Celal Bayar Üniversitesi Fen Bilimleri Dergisi / 2016 / CBUJOS, 2016, Volume 12, Issue 2

Microwave-assisted Synthesis of Some New Potential Biological 4-(Arylidenamino)-2, 4-dihydro-3H-1,2,4-Triazol-3-ones and Determination of pKa Values

BazıYeniPotansiyelBiyolojik 4-(Arylidenamino)-2, 4-dihidro-3H1,2,4-Triazol-3-one BileşiklerininMikrodalgadestekliSentezivepKaDeğerlerininBelirlenmesi

Bahittin KAHVECİ
İnci DOĞAN
Fatih İSLAMOĞLU
Fatih YILMAZ
Pages
275–281
Publication Date
2016-08-29
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The effects of solvents composition on the acid dissociation constants are discussed.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:In the present study, eight new 4-(arylideneamino)-2,4-dihydro-1H-1,2,4-triazol-3-ones that may show some potential biological properties were synthesized using microwave method.
📊
Key Findings & Data:These compounds were characterized by different spectroscopic techniques (IR, 1H NMR, 13C NMR and elemental analysis).
💡
Conclusion & Impact:The effects of solvents composition on the acid dissociation constants are discussed.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Asit ayrışma sabiti · 4-Amino-1 · 4-triazol

Abstract

In the present study, eight new 4-(arylideneamino)-2,4-dihydro-1H-1,2,4-triazol-3-ones that may show some potential biological properties were synthesized using microwave method. These compounds were characterized by different spectroscopic techniques (IR, 1H NMR, 13C NMR and elemental analysis). Acid dissociation constants (pKa) were determined theoretically with SPARC computer program in different twenty five solvents at 25oC. The effects of solvents composition on the acid dissociation constants are discussed.

Özet

Bu çalışmada,sekiz yeni bazı potansiyel biyolojik aktif 4-(arilidenamino)-2,4-dihidro-1H-1,2,4-triazol-3-on bileşikleri mikrodalga yöntemi kullanılarak sentezlendi. Bu bileşiklerin yapıları farklı spektroskopik yöntemle (IR, 1H NMR, 13C NMR and elemental analiz) kullanılarak karakterize edildi. Bu bileşiklerin asit ayrışma sabitleri teorik olarak 25oC’de yirmi beş farklı çözücü içerisinde SPARC bilgisayar programı vasıtasıyla belirlendi. Çözücülerin asit ayrışma sabitleri üzerindeki etkileri tartışıldı

🔖

Cite This Article

KAHVECİ, B., DOĞAN, İ., İSLAMOĞLU, F., YILMAZ, F. (2016). Microwave-assisted Synthesis of Some New Potential Biological 4-(Arylidenamino)-2, 4-dihydro-3H-1,2,4-Triazol-3-ones and Determination of pKa Values. Celal Bayar Üniversitesi Fen Bilimleri Dergisi, CBUJOS, 2016, Volume 12, Issue 2, 275–281. https://ajindex.com/articles/115966

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...