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Journals / Balıkesir Medical Journal / 2017 / Cilt: 1 Sayı: 3

The role of advanced magnetic resonance imaging techniques in a pediatric Progressive Multifocal Leukoencephalopathy patient associated with Bruton disease : The pediatric radiologist ‘s approach within a case report

Bruton hastalığı zemininde gelişen PML olgusuna pediatrik radyoloji açısından bakış

Mehmet Burak Ozkan
Meltem Ceyhan Bilgici
Alişan Yildiran
Pages
88–93
Publication Date
2017-12-18
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In this case report, our goal is to discuss the supportive findings and benefits of using advanced MR techniques in an immunocompromised pediatric patient suffering from PML disease.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:JC papovavirus, which is a neurotropic virus, causes a demyelinating process in oligodendrocytes.
📊
Key Findings & Data:Multivoxel spectroscopy revealed an increase in the Cho/Cr and mI/Cr ratios, and a decreased in the N-acetylaspartate (NAA) values.
💡
Conclusion & Impact:In this case report, our goal is to discuss the supportive findings and benefits of using advanced MR techniques in an immunocompromised pediatric patient suffering from PML disease.
🔬Design:Olgu Sunumu
📍Scope:Comprehensive Sample
⚙️Variables:pediatrik radyoloji · DTİ · MRİ

Abstract

JC papovavirus, which is a neurotropic virus, causes a demyelinating process in oligodendrocytes. Diffusion tensor imaging (DTI) showed white-matter tract interruptions in the right frontal hemispheric region. Multivoxel spectroscopy revealed an increase in the Cho/Cr and mI/Cr ratios, and a decreased in the N-acetylaspartate (NAA) values. These values show the demyelinating process and damage, whereas mI levels are known to be the predictor of the severity of the dis-ease. In this case report, our goal is to discuss the supportive findings and benefits of using advanced MR techniques in an immunocompromised pediatric patient suffering from PML disease.

Özet

Jc papovavirüs nörontropik virüs olup oligodendrositlerde demyelinizasyona neden olmaktadır. Difüzyon tensör incelemede beyaz cevher yolaklarında sağ frontal bölgede kesinti izlenmektedir. Multivoksel spektroskopi incelemede Cho/Cr ve mI/Cr oranlarında artış izlenirken NAA miktarlarında düşme izlenmektedir. Bu bulgular demyelinizan hasarı gösterir-ken, mI hastalığın şiddetini göstermektedir. Bizim bu çalışmada amacımız ileri MRG tekniklerini kullanarak immün yetmezlik olan bir olguda gelişen PML hastalığının bulgularını tartışmaktır.

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Cite This Article

Ozkan, M. B., Bilgici, M. C., Yildiran, A. (2017). The role of advanced magnetic resonance imaging techniques in a pediatric Progressive Multifocal Leukoencephalopathy patient associated with Bruton disease : The pediatric radiologist ‘s approach within a case report. Balıkesir Medical Journal, Cilt: 1 Sayı: 3, 88–93. https://ajindex.com/articles/1150911

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References (13)

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