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Journals / Turkish Journal of Medical Sciences / 2015 / Cilt: 45 - Sayı: 2

Comparison of the analgesic effects of paracetamol and tramadol in lumbar disc surgery

Mehmet Ziya YILMAZ
Bahriye Binnur SARIHASAN
Ebru KELSAKA
Nilay TAŞ
Aysun Çağlar TORUN
Ersin KÖKSAL
Enis KURUOĞLU
Pages
438–442
Publication Date
2015-08-13
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Tramadol was more effective in the treatment of postoperative pain after lumbar disc surgery.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Background/aim: To compare the postoperative analgesic efficacy and side effects of paracetamol and tramadol in patients undergoing lumbar disc surgery.
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Key Findings & Data:Materials and methods: Group P (paracetamol group) was given 1 g of paracetamol intravenously 30 min before the end of the operation and 1 g each day at 6-h intervals.
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Conclusion & Impact:Tramadol was more effective in the treatment of postoperative pain after lumbar disc surgery.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Paracetamol · tramadol · postoperative analgesia

Abstract

Background/aim: To compare the postoperative analgesic efficacy and side effects of paracetamol and tramadol in patients undergoing lumbar disc surgery. Materials and methods: Group P (paracetamol group) was given 1 g of paracetamol intravenously 30 min before the end of the operation and 1 g each day at 6-h intervals. Group T (tramadol group) was given 1.5 mg/kg of tramadol as a loading dose and patient-controlled analgesia for 1 day. Hemodynamic parameters, modified Aldrete score, Ramsay sedation scale score, patient satisfaction scale (PSS) score, visual analog scale (VAS) score, nausea/vomiting scale score, and additional analgesic needs/times were recorded. Results: PSS scores were significantly higher in Group T (P < 0.05). The total analgesic consumption was significantly higher in Group P. There were no significant differences in the VAS scores at any time points. Twenty-one patients in Group P and 8 patients in Group T needed additional analgesia (P < 0.05). The first additional analgesic time was earlier in Group P, and pain was more evident at the 15th minute and at hours 2 and 6 (P < 0.05). Conclusion: Paracetamol alone was not able to provide effective analgesia. Tramadol was more effective in the treatment of postoperative pain after lumbar disc surgery.

Özet

Background/aim: To compare the postoperative analgesic efficacy and side effects of paracetamol and tramadol in patients undergoing lumbar disc surgery. Materials and methods: Group P (paracetamol group) was given 1 g of paracetamol intravenously 30 min before the end of the operation and 1 g each day at 6-h intervals. Group T (tramadol group) was given 1.5 mg/kg of tramadol as a loading dose and patient-controlled analgesia for 1 day. Hemodynamic parameters, modified Aldrete score, Ramsay sedation scale score, patient satisfaction scale (PSS) score, visual analog scale (VAS) score, nausea/vomiting scale score, and additional analgesic needs/times were recorded. Results: PSS scores were significantly higher in Group T (P < 0.05). The total analgesic consumption was significantly higher in Group P. There were no significant differences in the VAS scores at any time points. Twenty-one patients in Group P and 8 patients in Group T needed additional analgesia (P < 0.05). The first additional analgesic time was earlier in Group P, and pain was more evident at the 15th minute and at hours 2 and 6 (P < 0.05). Conclusion: Paracetamol alone was not able to provide effective analgesia. Tramadol was more effective in the treatment of postoperative pain after lumbar disc surgery.

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Cite This Article

YILMAZ, M. Z., SARIHASAN, B. B., KELSAKA, E., TAŞ, N., TORUN, A. Ç., KÖKSAL, E., KURUOĞLU, E. (2015). Comparison of the analgesic effects of paracetamol and tramadol in lumbar disc surgery. Turkish Journal of Medical Sciences, Cilt: 45 - Sayı: 2, 438–442. https://ajindex.com/articles/114018

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