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Journals / Turkish Journal of Medical Sciences / 2015 / Cilt: 45 - Sayı: 3

Clinical characteristics of 75 pandemic H1N1 influenza patientsfrom Turkey; risk factors for fatality

HATİCE KILIÇ
ASİYE KANBAY
AYŞEGÜL KARALEZLİ
HATİCE CANAN HASANOĞLU
CAN ATEŞ
Pages
562–567
Publication Date
2015-08-13
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: Increased D-dimer levels were observed in pneumonia patients with H1N1 infection, which predicted the severity of pneumonia.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Background/aim: The 2009 influenza A (H1N1) pandemic caused mild to severe illnesses and led to death in some cases.
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Key Findings & Data:In this study, we aimed to evaluate the relationship between the serum D-dimer levels, CURB-65 scores, and the severity of pneumonia among patients with H1N1 infections.
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Conclusion & Impact:Conclusion: Increased D-dimer levels were observed in pneumonia patients with H1N1 infection, which predicted the severity of pneumonia.
🔬Design:Research Article
📍Scope:2009 Verileri
⚙️Variables:H1N1 · pneumonia severity index · pneumonia

Abstract

Background/aim: The 2009 influenza A (H1N1) pandemic caused mild to severe illnesses and led to death in some cases. In this study, we aimed to evaluate the relationship between the serum D-dimer levels, CURB-65 scores, and the severity of pneumonia among patients with H1N1 infections. Materials and methods: Sixty-eight patients who had probable H1N1 infections were evaluated by clinical, radiological, and laboratory methods. The H1N1 strain was specified by reverse transcription-polymerase chain reaction. Of 55 patients diagnosed with pneumonia, 18 exhibited H1N1 positivity and 37 patients did not. Results: CURB-65 scores of pneumonia patients with H1N1 (group 1) were higher than those of patients without H1N1 (group 2) (P = 0.02). The D-dimer levels of group 1 were higher than those of group 2 (P = 0.001). Moreover, there was a positive correlation between D-dimer levels and CURB-65 scores in patients with H1N1-associated pneumonia (P = 0.001; r = 0.89). Conclusion: Increased D-dimer levels were observed in pneumonia patients with H1N1 infection, which predicted the severity of pneumonia.

Özet

Background/aim: The 2009 influenza A (H1N1) pandemic caused mild to severe illnesses and led to death in some cases. In this study, we aimed to evaluate the relationship between the serum D-dimer levels, CURB-65 scores, and the severity of pneumonia among patients with H1N1 infections. Materials and methods: Sixty-eight patients who had probable H1N1 infections were evaluated by clinical, radiological, and laboratory methods. The H1N1 strain was specified by reverse transcription-polymerase chain reaction. Of 55 patients diagnosed with pneumonia, 18 exhibited H1N1 positivity and 37 patients did not. Results: CURB-65 scores of pneumonia patients with H1N1 (group 1) were higher than those of patients without H1N1 (group 2) (P = 0.02). The D-dimer levels of group 1 were higher than those of group 2 (P = 0.001). Moreover, there was a positive correlation between D-dimer levels and CURB-65 scores in patients with H1N1-associated pneumonia (P = 0.001; r = 0.89). Conclusion: Increased D-dimer levels were observed in pneumonia patients with H1N1 infection, which predicted the severity of pneumonia.

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Cite This Article

KILIÇ, H., KANBAY, A., KARALEZLİ, A., HASANOĞLU, H. C., ATEŞ, C. (2015). Clinical characteristics of 75 pandemic H1N1 influenza patientsfrom Turkey; risk factors for fatality. Turkish Journal of Medical Sciences, Cilt: 45 - Sayı: 3, 562–567. https://ajindex.com/articles/113927

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