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Journals / Experimed / 2026 / Volume: 14 Issue: 2

Apelin Levels According to the Site of Involvement in Inflammatory Bowel Diseases

Ezgi Değerli(University of Health Sciences, Bakirkoy Dr. Sadi Konuk Training and Research Hospital, Department of Medical Oncology)0000-0002-8664-5701
Selcan Cesur(Eskisehir City Hospital, Department of Gastroenterology)0000-0002-1504-7069
Ahmet Yavuz(Diyarbakir Gazi Yasargil Training and Research Hospital, Department of Gastroenterology)0000-0002-4633-5012
Mahmut Said Değerli(UNIVERSITY OF HEALTH SCIENCES, İSTANBUL BAKIRKÖY DR. SADİ KONUK TRAINING RESEARCH CENTER, DEPARTMENT OF SURGICAL MEDICAL SCIENCES, DEPARTMENT OF GENERAL SURGERY)0000-0002-8313-7904
Zeynep Ermiş Karaali(Basaksehir Cam and Sakura City Hospital, Department of Internal Medicine)0000-0002-3770-287X
Journal
Experimed
Pages
—
Publication Date
2024-08-26
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Future research on apelin and IBD could refine its utility in disease monitoring and enhance its diagnostic significance.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: Inflammatory bowel disease (IBD), including ulcerative colitis (UC) and Crohn’s disease (CD), presents ongoing challenges in terms of diagnosis and management.
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Key Findings & Data:Materials and Methods: The study included 91 patients who were followed up for IBD.
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Conclusion & Impact:Future research on apelin and IBD could refine its utility in disease monitoring and enhance its diagnostic significance.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Inflammatory bowel disease · apelin · Crohn

Abstract

Objective: Inflammatory bowel disease (IBD), including ulcerative colitis (UC) and Crohn’s disease (CD), presents ongoing challenges in terms of diagnosis and management. With increasing treatment options, reliable markers for assessing treatment response have become crucial. This study explored the potential of apelin, a peptide hormone implicated in inflammation, as a biomarker for monitoring disease activity in patients with IBD undergoing colonoscopy. Materials and Methods: The study included 91 patients who were followed up for IBD. Apelin levels were measured in serum, and the site of involvement was simultaneously examined by colonoscopy. Alternations of apelin levels depending on the location of involvement was also considered. Results: Despite the widespread presence of apelin in the gastrointestinal system (GIS), our findings did not reveal significant differences in apelin levels among patients with varying colonoscopic involvement (p=0.73). Conclusion: Although apelin has potential as a biomarker of gastrointestinal inflammation in IBD, its precise role and clinical applicability necessitate comprehensive studies involving larger patient populations. Future research on apelin and IBD could refine its utility in disease monitoring and enhance its diagnostic significance.

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Cite This Article

Değerli, E., Cesur, S., Yavuz, A., Değerli, M. S., Karaali, Z. E. (2024). Apelin Levels According to the Site of Involvement in Inflammatory Bowel Diseases. Experimed, Volume: 14 Issue: 2. https://doi.org/10.26650/experimed.1494644

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