Journals / İstanbul Tıp Fakültesi Dergisi / 2026 / Cilt: 88 Sayı: 1

MEASLES-MUMPS-RUBELLA VACCINATION IN A PAEDIATRIC TRANSPLANT PATIENT USING EVEROLIMUS

EVEROLIMUS KULLANAN BİR PEDİATRİK TRANSPLANT OLGUSUNDA KIZAMIK-KABAKULAK-KIZAMIKÇIK AŞISI UYGULAMASI

Aybüke Kaçır(ISTANBUL MEDIPOL UNIVERSITY, INTERNATIONAL FACULTY OF MEDICINE, DEPARTMENT OF INTERNAL MEDICINE, DEPARTMENT OF PEDIATRICS, SOCIAL PEDIATRICS)0009-0002-3474-5863
Övgü Büke(ISTANBUL MEDIPOL UNIVERSITY, INTERNATIONAL FACULTY OF MEDICINE, DEPARTMENT OF INTERNAL MEDICINE, DEPARTMENT OF PEDIATRICS, SOCIAL PEDIATRICS)0000-0002-3922-2976
Nalan Karabayır(ISTANBUL MEDIPOL UNIVERSITY, INTERNATIONAL FACULTY OF MEDICINE, DEPARTMENT OF INTERNAL MEDICINE, DEPARTMENT OF PEDIATRICS, SOCIAL PEDIATRICS)0000-0002-8003-1952
Mine Başıbüyük(ISTANBUL MEDIPOL UNIVERSITY, INTERNATIONAL FACULTY OF MEDICINE, DEPARTMENT OF INTERNAL MEDICINE, DEPARTMENT OF PEDIATRICS, SOCIAL PEDIATRICS)0000-0002-9159-4961
Demet Deniz Bilgin(ISTANBUL MEDIPOL UNIVERSITY, INTERNATIONAL FACULTY OF MEDICINE, DEPARTMENT OF INTERNAL MEDICINE, DEPARTMENT OF PEDIATRICS, SOCIAL PEDIATRICS)0000-0002-9794-9460
Özlem Öcal(ISTANBUL MEDIPOL UNIVERSITY, INTERNATIONAL FACULTY OF MEDICINE, DEPARTMENT OF INTERNAL MEDICINE, DEPARTMENT OF PEDIATRICS, SOCIAL PEDIATRICS)0000-0002-4210-2430
Pages
80–82
Publication Date
2025-01-31
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

This article presents a case of paediatric solid organ transplantation patient who received a measles-mumps-rubella vaccination while receiving immunosuppressive everolimus therapy.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:There is limited information regarding the administration of live vaccines to paediatric transplant patients who are at increased risk of infection.
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Key Findings & Data:A 7-year-old liver transplant patient who had everolimus therapy was evaluated for Measles-Mumps-Rubella (MMR) vaccination.
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Conclusion & Impact:This article presents a case of paediatric solid organ transplantation patient who received a measles-mumps-rubella vaccination while receiving immunosuppressive everolimus therapy.
🔬Design:Olgu Sunumu
📍Scope:Comprehensive Sample
⚙️Variables:Çocuk · aşılama · everolimus

Abstract

There is limited information regarding the administration of live vaccines to paediatric transplant patients who are at increased risk of infection. A 7-year-old liver transplant patient who had everolimus therapy was evaluated for Measles-Mumps-Rubella (MMR) vaccination. After checking the lymphocyte count, immunoglobulin G, and serum everolimus levels, the MMR vaccine was administered. No side effects were observed during follow-up, and the antibody levels were found to be positive after two months. This article presents a case of paediatric solid organ transplantation patient who received a measles-mumps-rubella vaccination while receiving immunosuppressive everolimus therapy.

Özet

İnfeksiyon riskinin artmış olduğu pediatrik transplantasyon hastalarında canlı aşıların uygulanması ile ilgili bilgiler sınırlı dır. Yedi yaşında, halen evorolimus kullanmakta olan karaciğer nakli hastası Kızamık-Kabakulak-Kızamıkçık (KKK) aşısı yapılmak amacıyla değerlendirildi. Lenfosit sayısı, immünoglobulin G ve serum everolimus düzeyleri kontrol edildikten sonra KKK aşısı uygulandı. İzlemde yan etki saptanmayan olguda, iki ay sonra bakılan antikor düzeyleri pozitif bulundu. Bu yazıda immüno supresif everolimus tedavisi alırken Kızamık-Kabakulak-Kıza mıkçık aşısı uygulanan bir pediatrik solid organ nakli olgusu sunulmaktadır.

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Cite This Article

Kaçır, A., Büke, Ö., Karabayır, N., Başıbüyük, M., Bilgin, D. D., Öcal, Ö. (2025). MEASLES-MUMPS-RUBELLA VACCINATION IN A PAEDIATRIC TRANSPLANT PATIENT USING EVEROLIMUS. İstanbul Tıp Fakültesi Dergisi, Cilt: 88 Sayı: 1, 80–82. https://doi.org/10.26650/IUITFD.1509646

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