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Journals / İstanbul Tıp Fakültesi Dergisi / 2026 / Cilt: 88 Sayı: 2

SPONTANEOUS DISAPPEARANCE OF A CAUDATE NUCLEUS ARTERIOVENOUS MALFORMATION FOLLOWING EXTERNAL VENTRICULAR DRAINAGE: A CASE REPORT AND LITERATURE REVIEW

Duygu Dölen(ISTANBUL UNIVERSITY, İSTANBUL FACULTY OF MEDICINE, DEPARTMENT OF SURGICAL MEDICAL SCIENCES, DEPARTMENT OF NEUROSURGERY)0000-0002-6929-4401
Sefa Öztürk(ISTANBUL UNIVERSITY, İSTANBUL FACULTY OF MEDICINE, DEPARTMENT OF SURGICAL MEDICAL SCIENCES, DEPARTMENT OF NEUROSURGERY)0000-0001-5583-0384
Alperen Poyraz(ISTANBUL UNIVERSITY, İSTANBUL FACULTY OF MEDICINE, DEPARTMENT OF SURGICAL MEDICAL SCIENCES, DEPARTMENT OF NEUROSURGERY)0000-0002-3885-5894
Cafer İkbal Gülsever(ISTANBUL UNIVERSITY, İSTANBUL FACULTY OF MEDICINE, DEPARTMENT OF SURGICAL MEDICAL SCIENCES, DEPARTMENT OF NEUROSURGERY)0000-0002-9246-1378
Tuğrul Cem Ünal(ISTANBUL UNIVERSITY, İSTANBUL FACULTY OF MEDICINE, DEPARTMENT OF SURGICAL MEDICAL SCIENCES, DEPARTMENT OF NEUROSURGERY)0000-0001-6228-1379
İlyas Dolaş(ISTANBUL UNIVERSITY, İSTANBUL FACULTY OF MEDICINE, DEPARTMENT OF SURGICAL MEDICAL SCIENCES, DEPARTMENT OF NEUROSURGERY)0000-0002-3425-3220
Mehmet Barburoğlu(ISTANBUL UNIVERSITY, İSTANBUL FACULTY OF MEDICINE, DEPARTMENT OF INTERNAL MEDICINE, DEPARTMENT OF RADIODIAGNOSTICS, NEURORADIOLOGY)0000-0002-8715-1893
Pulat Akın Sabancı(ISTANBUL UNIVERSITY, İSTANBUL FACULTY OF MEDICINE, DEPARTMENT OF SURGICAL MEDICAL SCIENCES, DEPARTMENT OF NEUROSURGERY)0000-0002-0283-0927
Pages
172–175
Publication Date
2025-04-28
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

While spontaneous resolution is possible, longterm imaging follow-up is essential due to the risk of delayed recanalization.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Brain arteriovenous malformations (AVMs) are congenital vascular anomalies that can cause life-threatening haemorrhages.
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Key Findings & Data:A 15-year-old female presented with severe headache and confusion.
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Conclusion & Impact:While spontaneous resolution is possible, longterm imaging follow-up is essential due to the risk of delayed recanalization.
🔬Design:Olgu Sunumu
📍Scope:Comprehensive Sample
⚙️Variables:Arteriovenöz malformasyon · eksternal ventriküler drenaj · intraventriküler kanama

Abstract

Brain arteriovenous malformations (AVMs) are congenital vascular anomalies that can cause life-threatening haemorrhages. Spontaneous AVM thrombosis is extremely rare and is not fully understood. A 15-year-old female presented with severe headache and confusion. Computed tomography (CT) revealed intraventricular haemorrhage, leading to urgent external ventricular drainage (EVD). Digital subtraction angiography (DSA) confirmed an AVM located in the right caudate nucleus head, supplied by the lateral lenticulostriate artery and draining into the deep venous system. At the 2-month follow-up, DSA showed complete disappearance of the AVM. This case highlights the rare phenomenon of spontaneous AVM thrombosis, potentially influenced by haemorrhage, venous outflow obstruction, and EVD placement. While spontaneous resolution is possible, longterm imaging follow-up is essential due to the risk of delayed recanalization.

Özet

Beyin arteriovenöz malformasyonları (AVM), yaşamı tehdit eden kanamalara yol açabilen konjenital vasküler anomalilerdir. AVM’lerin kendiliğinden tromboze olması son derece nadir görülen ve yeterince anlaşılamayan bir durumdur. On beş yaşında bir kız hasta, şiddetli baş ağrısı ve bilinç bulanıklığı ile acil servise başvurdu. Bilgisayarlı tomografi (BT), intraventriküler kanama gösterdi ve acil eksternal ventriküler drenaj (EVD) uygulandı. Dijital substraksiyon anjiyografi (DSA), sağ kaudat çekirdek başına yerleşmiş, lateral lentikülostriat arter tarafından beslenen ve derin venöz sisteme drene olan bir AVM saptadı. İki ay sonra yapılan kontrol DSA’da AVM’nin tamamen kaybolduğu gözlendi ve kendiliğinden tromboz geliştiği düşünüldü. Bu olgu, kanama, venöz drenaj tıkanıklığı ve EVD uygulamasının AVM trombozunu nasıl tetikleyebileceğini gösteren nadir bir örnektir. AVM’lerin kendiliğinden kaybolması mümkün olmakla birlikte, geç rekürrens riski nedeniyle uzun süreli görüntüleme takibi gereklidir.

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Cite This Article

Dölen, D., Öztürk, S., Poyraz, A., Gülsever, C. İ., Ünal, T. C., Dolaş, İ., Barburoğlu, M., Sabancı, P. A. (2025). SPONTANEOUS DISAPPEARANCE OF A CAUDATE NUCLEUS ARTERIOVENOUS MALFORMATION FOLLOWING EXTERNAL VENTRICULAR DRAINAGE: A CASE REPORT AND LITERATURE REVIEW. İstanbul Tıp Fakültesi Dergisi, Cilt: 88 Sayı: 2, 172–175. https://doi.org/10.26650/IUITFD.1623147

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