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Journals / Journal of Microbiology and Infectious Diseases / 2026 / Cilt: 2 Sayı: 01

The follow-up results with sustained virologic response in chronic hepatitisC patients in Sanliurfa/Turkey

Suda Tekin Koruk
İbrahim Koruk
Celal Calisir
Hasan Karsen
Pages
14–20
Publication Date
2012-03-01
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

Conclusions: In conclusion, there was no recurrence of HCV infection beyond follow-up of 24 months in any of the patients who obtained SVR.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objectives: The aim of the study was to evaluate sustained virological response (SVR) after treatment and factors that influence SVR among patients treated for chronic hepatitis C (CHC).
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Key Findings & Data:Materials and methods: The study was conducted in patients with CHC between April 2007 and March 2011, who had achieved SVR following treatment.
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Conclusion & Impact:Conclusions: In conclusion, there was no recurrence of HCV infection beyond follow-up of 24 months in any of the patients who obtained SVR.
🔬Design:Makale
📍Scope:2007 Verileri
⚙️Variables:Chronic hepatitis C · genotype · sustained virological response

Abstract

Objectives: The aim of the study was to evaluate sustained virological response (SVR) after treatment and factors that influence SVR among patients treated for chronic hepatitis C (CHC). Materials and methods: The study was conducted in patients with CHC between April 2007 and March 2011, who had achieved SVR following treatment. They were treated with PEG IFN-&alpha; and ribavirin. Patients, whose end of treatment responses were obtained without a SVR, received a second course of treatment. Results: A total of 124 patients, 61 female (49.2%) were enrolled in the study. The distribution of genotypes was: 102 patients with genotype 1 (82.3%) and 22 with genotype 2 (17.7%). SVR was achieved in 78 patients (62.9%) (67 during the first course and 11 in the second) were followed up for a mean duration of 18.4&plusmn;8.5 months. Positive predictive factors on SVR were female gender (P=0.01), low initial viral load (P=0.01), early virological response (EVR) development (P<0.001) and infection with genotype 2 (P<0.001). Conclusions: In conclusion, there was no recurrence of HCV infection beyond follow-up of 24 months in any of the patients who obtained SVR. Female gender, low initial viral load, development of EVR and infection with genotype 2 was determined to have a positive impact on SVR.

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Cite This Article

Koruk, S. T., Koruk, İ., Calisir, C., Karsen, H. (2012). The follow-up results with sustained virologic response in chronic hepatitisC patients in Sanliurfa/Turkey. Journal of Microbiology and Infectious Diseases, Cilt: 2 Sayı: 01, 14–20. https://doi.org/10.5799/ahinjs.02.2012.01.0035

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