In this study, potentially biological active new Schiff bases were synthesized in good yield from 1-amino-4-methylpiperazine and aromatic aldehydes as a 3-nitro-benzaldehyde, 4-fluoro-benzaldehyde, 3,4,5-trimethoxybenzaldehyde, 3,4-dichlorobenzaldehyde, 4-diethylaminobenzaldehyde, 2,5-dimethoxybenzaldehyde and 5-nitro-2-furaldehyde and structure of the synthesized compounds were elucidated by FTIR, LC-MS, 1 H-NMR and 13 C-NMR techniques.
📌 3 Key Takeaways
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Objective & Hypothesis:In this study, potentially biological active new Schiff bases were synthesized in good yield from 1-amino-4-methylpiperazine and aromatic aldehydes as a 3-nitro-benzaldehyde, 4-fluoro-benzaldehyde, 3,4,5-trimethoxybenzaldehyde, 3,4-dichlorobenzaldehyde, 4-diethylaminobenzaldehyde, 2,5-dimethoxybenzaldehyde and 5-nitro-2-furaldehyde and structure of the synthesized compounds were elucidated by FTIR, LC-MS, 1 H-NMR and 13 C-NMR techniques.
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Key Findings & Data:In this study, potentially biological active new Schiff bases were synthesized in good yield from 1-amino-4-methylpiperazine and aromatic aldehydes as a 3-nitro-benzaldehyde, 4-fluoro-benzaldehyde, 3,4,5-trimethoxybenzaldehyde, 3,4-dichlorobenzaldehyde, 4-diethylaminobenzaldehyde, 2,5-dimethoxybenzaldehyde and 5-nitro-2-furaldehyde and structure of the synthesized compounds were elucidated by FTIR, LC-MS, 1 H-NMR and 13 C-NMR techniques.
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Conclusion & Impact:In this study, potentially biological active new Schiff bases were synthesized in good yield from 1-amino-4-methylpiperazine and aromatic aldehydes as a 3-nitro-benzaldehyde, 4-fluoro-benzaldehyde, 3,4,5-trimethoxybenzaldehyde, 3,4-dichlorobenzaldehyde, 4-diethylaminobenzaldehyde, 2,5-dimethoxybenzaldehyde and 5-nitro-2-furaldehyde and structure of the synthesized compounds were elucidated by FTIR, LC-MS, 1 H-NMR and 13 C-NMR techniques.
In this study, potentially biological active new Schiff bases were synthesized in good yield from 1-amino-4-methylpiperazine and aromatic aldehydes as a 3-nitro-benzaldehyde, 4-fluoro-benzaldehyde, 3,4,5-trimethoxybenzaldehyde, 3,4-dichlorobenzaldehyde, 4-diethylaminobenzaldehyde, 2,5-dimethoxybenzaldehyde and 5-nitro-2-furaldehyde and structure of the synthesized compounds were elucidated by FTIR, LC-MS, 1 H-NMR and 13 C-NMR techniques.
Ay, E. (2016). Synthesis and Characterization of Schiff Base 1-Amino-4-methylpiperazine Derivatives. Celal Bayar Üniversitesi Fen Bilimleri Dergisi, Cilt: 12 Sayı: 3, 375–392. https://doi.org/10.18466/cbayarfbe.280600