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Journals / Harran Üniversitesi Tıp Fakültesi Dergisi / 2014 / Cilt: 11 - Sayı: 3

Henoch-Schönlein Purpura induced by Low-Dose Methotrexate

Düşük doz Methotrexatın indüklediği Henoch-Schönlein Purpurası

İrfan KOCA
Mehmet UCAR
Ahmet TUTOGLU
Ayse BERHOGLU
Ahmet BOYACİ
Pages
316–320
Publication Date
2014-12-15
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

In this paper, we presented together with a review of the literature a case of HSP that developed in the third week of treatment of a 14-year-old male patient started on low-dose methotrexate for juvenile idiopathic arthritis.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Methotrexate (MTX) is an antiproliferative folic acid antagonist used in the treatment of various malignancies and chronic inflammatory diseases.
📊
Key Findings & Data:Commonly observed side effects in patients receiving lowdose, weekly MTX treatment are nausea and stomatitis.
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Conclusion & Impact:In this paper, we presented together with a review of the literature a case of HSP that developed in the third week of treatment of a 14-year-old male patient started on low-dose methotrexate for juvenile idiopathic arthritis.
🔬Design:Review & Systematic Survey
📍Scope:Comprehensive Sample
⚙️Variables:Henoch-Schönlein Purpura · Juvenile Idiopathic Artrit · Metotreksa

Abstract

Methotrexate (MTX) is an antiproliferative folic acid antagonist used in the treatment of various malignancies and chronic inflammatory diseases. Commonly observed side effects in patients receiving lowdose, weekly MTX treatment are nausea and stomatitis. Henoch-Schönlein purpura (HSP) is a condition generally induced by infectious agents, exposure to cold, insect bites, foods, and drugs. In this paper, we presented together with a review of the literature a case of HSP that developed in the third week of treatment of a 14-year-old male patient started on low-dose methotrexate for juvenile idiopathic arthritis.

Özet

Metotreksat (MTX), çeşitli malignite ve kronik inflamatuvar hastalıkların tedavisinde kullanılan antiproliferatif bir folik asit antagonistidir. Düsük doz, haftalık MTX tedavisi alan hastalarda sık görülen yan etkiler bulantı ve stomatittir. Henoch-Schönlein purpurası (HSP) genellikle, infeksiyon ajanları, soğuk, böcek ısırması, besinler veya ilaçlara bağlı olarak tetiklenir. Bu yazıda juvenil idiyopatik artrite yönelik düşük doz metotrexate başlanan 14 yaşındaki erkek hastada tedavinin 3. haftasında ortaya çıkan HSP literatür eşliğinde sunulmuştur.

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Cite This Article

KOCA, İ., UCAR, M., TUTOGLU, A., BERHOGLU, A., BOYACİ, A. (2014). Henoch-Schönlein Purpura induced by Low-Dose Methotrexate. Harran Üniversitesi Tıp Fakültesi Dergisi, Cilt: 11 - Sayı: 3, 316–320. https://ajindex.com/articles/109724

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References (9)

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