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Journals / Harran Üniversitesi Tıp Fakültesi Dergisi / 2018 / Cilt: 15 Sayı: 3

Comparison of pregnancy and neonatal outcome in spontaneous and invitro fertilization (IVF) twin pregnancies

Spontan ve invitro fertilizasyon ikiz gebeliklerinde gebeliğe ait ve neonatal verilerin karşılaştırılması

Coşkun Şimşir0000-0003-1825-6584
Ziya Kalem0000-0002-5435-2074
Batuhan Bakırarar(ANKARA UNIVERSITY)0000-0002-5662-8193
Muberra Namlı Kalem0000-0002-2316-5495
Pages
250–254
Publication Date
2018-12-12
DOI
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: In conclusion, it was shown in this study that the risks of preterm birth and low birthweight which are already higher in twin pregnancies than in singleton pregnancies were even higher in the IVF twin pregnancies.

📌 3 Key Takeaways

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Objective & Hypothesis:Background: This study aimed to investigate whether the differences between twin invitrofertilization (IVF) and twin spontaneous pregnancies in terms of pregnancy and perinatal outcome.
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Key Findings & Data:Material and Methods: This is a retrospective cohort study carried out by examining the data of dichorionic-diamniotic twin pregnancies with live births in a private hospital between 2015 and 2018.
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Conclusion & Impact:Conclusion: In conclusion, it was shown in this study that the risks of preterm birth and low birthweight which are already higher in twin pregnancies than in singleton pregnancies were even higher in the IVF twin pregnancies.
🔬Design:Araştırma Makalesi
📍Scope:2015 Verileri
⚙️Variables:IVF · İkiz gebelikler · tekil gebelikler

Abstract

Background: This study aimed to investigate whether the differences between twin invitrofertilization (IVF) and twin spontaneous pregnancies in terms of pregnancy and perinatal outcome. Material and Methods: This is a retrospective cohort study carried out by examining the data of dichorionic-diamniotic twin pregnancies with live births in a private hospital between 2015 and 2018. There were two study groups which were the twin pregnancy group with spontaneous pregnancy and the IVF twin group with pregnancy via assisted reproductive techniques. Results: Pregnancy and birth problems did not differ between the two groups. The IVF twin pregnancies were observed to have higher rates of preterm birth, low birthweight and APGAR 1st minute scores. Perinatal mortality rates were found similar in both groups. Conclusion: In conclusion, it was shown in this study that the risks of preterm birth and low birthweight which are already higher in twin pregnancies than in singleton pregnancies were even higher in the IVF twin pregnancies. It is recommended in accordance with these results that single embryo transfers should be preferred and iatrogenic multiple pregnancies should not be encouraged.

Özet

Amaç: Bu çalışmanın amacı invitro fertizasyon(IVF) tedavisi ile gerçekleşen ikiz gebelikler ile spontan gerçekleşen ikiz gebeliklerin gebelik ve perinatal dönem bulguları açısından karşılaştırılmasıdır. Materyal ve Method: Bu çalışma, 2015-2018 yılları arasında, canlı doğumu gerçekleşen dikoryonik diamniotik ikiz gebeliklerin verileri incelenerek gerçekleştirilmiş bir retrospektif kohort çalışmasıdır. Bu araştırmada gebeliği spontan olarak gerçekleşmiş ikiz gebelikler grubu ve yardımcı üreme teknikleri kullanılarak gebe kalmış IVF ikiz grubu olmak üzere iki çalışma grubu vardır Bulgular: Gebeliğe ve doğuma ait problemler her iki grup arasında farklılık göstermemiştir. IVF ikiz gebeliklerinde prematurite, düşük doğum ağırlığı ve 1. Dakika APGAR skor düşüklüğü oranlarının daha fazla olduğu görülmüştür. Perinatal mortalite oranları her iki grupta benzer bulunmuştur. Sonuç: Bu çalışmada gösterilmiştir ki; ikiz gebeliklerde tek gebeliklere göre zaten daha yüksek riske sahip olan erken doğum ve düşük doğum ağırlığı riskleri, IVF ikiz gebeliklerinde daha da fazla artmaktadır. Bu sonuçlar gözönüne alınarak tek embryo transferine yönelmek ve iatrojenik çoğul gebeliklere destek vermemek önerilmelidir.

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Cite This Article

Şimşir, C., Kalem, Z., Bakırarar, B., Kalem, M. N. (2018). Comparison of pregnancy and neonatal outcome in spontaneous and invitro fertilization (IVF) twin pregnancies. Harran Üniversitesi Tıp Fakültesi Dergisi, Cilt: 15 Sayı: 3, 250–254. https://ajindex.com/articles/1081531

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