Journals / Harran Üniversitesi Tıp Fakültesi Dergisi / 2023 / Cilt: 20 Sayı: 3

Geri Çekildi: The Importance of Lactate Dehydrogenase Levels in COVID-19 Pneumonia

Geri Çekildi: COVİD-19 Pnömonisinde Laktat Dehidrogenaz Düzeylerinin Önemi

Zeliha Demir Giden(viranşehir devlet hastanesi)
Ramazan Giden(HARRAN ÜNİVERSİTESİ)0000-0003-2127-1056
Elif Demir(HARRAN ÜNİVERSİTESİ)0000-0003-4545-5175
Pages
695–699
Publication Date
2023-12-31
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: As a result of this study, the idea that the lactate dehydrogenas levels of the patients at the time of first admission may be useful in predicting COVID-19 pneumonia in healthcare institutions without computed tomography and in patient groups where computed tomography scan is not recommended, and in healthcare institutions with computed tomography, lactate dehydrogenas value is high in COVID-19 patients, computed tomography screening made us think that it can give an idea about the decision.

📌 3 Key Takeaways

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Objective & Hypothesis:Background: Our aim in this study is to determine how lactate dehydrogenas levels are affected in RT-PCR positive COVID-19 pneumonia.
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Key Findings & Data:Material and Methods: One hundred COVID-19 patients admitted to the hospital with positive RT-PCR test and above the age of 18 were included in our study.
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Conclusion & Impact:Conclusion: As a result of this study, the idea that the lactate dehydrogenas levels of the patients at the time of first admission may be useful in predicting COVID-19 pneumonia in healthcare institutions without computed tomography and in patient groups where computed tomography scan is not recommended, and in healthcare institutions with computed tomography, lactate dehydrogenas value is high in COVID-19 patients, computed tomography screening made us think that it can give an idea about the decision.
🔬Design:Sayıdan Geri Çekildi
📍Scope:Comprehensive Sample
⚙️Variables:COVID-19 · pnömoni · laktat dehidrogenaz

Abstract

Background: Our aim in this study is to determine how lactate dehydrogenas levels are affected in RT-PCR positive COVID-19 pneumonia. To investigate the value of this parameter in terms of biochemical parameters in RT-PCR positive patients and to propose new opinions on the subject. Material and Methods: One hundred COVID-19 patients admitted to the hospital with positive RT-PCR test and above the age of 18 were included in our study. The data of the patients were collected retrospectively from the hospital system. RT-PCR positive patients were divided into two groups as those with COVID-19 pneumonia and those without COVID-19 pneumonia. The obtained results were evaluated in the SPSS 25 program. Results: Of the 100 patients with positive RT-PCR test, 39 did not have COVID-19 pneumonia, 61 had COVID-19 pneumonia. Lactate dehydrogenas levels of patients with COVID-19 pneumonia was significantly higher than lactate dehydrogenas levels of patients without COVID-19 pneumonia (198.91 ± 141.34, 194.18 ± 69.19, p = 0.001). Conclusion: As a result of this study, the idea that the lactate dehydrogenas levels of the patients at the time of first admission may be useful in predicting COVID-19 pneumonia in healthcare institutions without computed tomography and in patient groups where computed tomography scan is not recommended, and in healthcare institutions with computed tomography, lactate dehydrogenas value is high in COVID-19 patients, computed tomography screening made us think that it can give an idea about the decision.

Özet

Amaç: Bu çalışmadaki amacımız, RT-PCR testi pozitif COVID-19 pömonisinde laktat dehidrogenaz seviyelerinin nasıl etkilendiğini tespit etmek. Bu parametrenin RT-PCR testi pozitif hastalarda biyokimyasal parametre açısından değerini araştırmak, konuyla ilgili yeni görüşler ileri sürebilmektir. Materyal ve Metod: Çalışmamıza hastaneye başvuran 18 yaş üstü RT-PCR testi pozitif olup servise yatışı olan 100 COVİD-19 hasta dahil edildi. Hastaların verileri hastanenin sisteminden geriye dönük olarak toplandı. RT-PCR pozitif hastalar COVİD-19 pnömonisi olan ve COVİD-19 pnömonisi olmayan olarak iki gruba ayrıldı. Elde edilen sonuçlar SPSS 25 programında değerlendirildi. Bulgular: RT-PCR testi pozitif olan 100 hastanın 39'unda COVİD-19 pnömonisi yoktu, 61'inde COVİD-19 pnömonisi vardı. COVİD-19 pnömonisi olan hastaların laktat dehidrogenaz değeri, COVİD-19 pnömonisi olmayan hastaların laktat dehidrogenaz değerinden anlamlı derecede yüksekti (198.91±141.34, 194.18±69.19, p=0.001). Sonuç: Yaptığımız çalışmada COVİD-19 pnömonisi olan hastalarda olmayanlara göre laktat dehidrogenaz değeri anlamlı derecede daha yüksek bulunmuştur. Bu yüzden çalışmamız hastaların ilk başvuru anındaki laktat dehidrogenaz değerlerinin bilgisayarlı tomografinin olmadığı sağlık kuruluşlarında ve bilgisayarlı tomografi çekiminin önerilmediği hasta gruplarında COVİD-19 pnömonisini öngörmede kullanılmasının faydalı olabileceği fikrini akla getirmiş ve bilgisayarlı tomografi olan sağlık kuruluşlarında ise COVİD-19 hastalarında laktat dehidrogenaz değerinin yüksek çıkması bilgisayarlı tomografi taraması kararını vermede fikir verebileceğini düşündürmüştür.

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Cite This Article

Giden, Z. D., Giden, R., Demir, E., *, Z. D. G. (2023). Geri Çekildi: The Importance of Lactate Dehydrogenase Levels in COVID-19 Pneumonia. Harran Üniversitesi Tıp Fakültesi Dergisi, Cilt: 20 Sayı: 3, 695–699. https://ajindex.com/articles/1081097

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References (2)

  1. Referans1 Huang C, Wang Y, Li X, Ren L, Zhao J, Hu Y. Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. Lancet. 2020;395:497–506. doi: 10.1016/S0140-6736(20)30183-5.
  2. Referans2 Zaman MK, White DA. Serum lactate dehydrogenase levels and Pneumocystis carinii pneumonia. Diagnostic and prognostic significance. Am. Rev. Respir. Dis. 1988;137:796–800.