Journals / ODÜ Tıp Dergisi / 2026 / Cilt: 12 Sayı: 1

Sleep-Related Headache Following Metformin Use: Hypnic or Toxic?

Metformin Sonrası Gelişen Uykuya Özgü Baş Ağrısı: Hipnik mi, Toksik mi?

Pages
14–18
Publication Date
2025-04-30
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

It underscores the importance of considering uncommon side effects of commonly prescribed medications, such as metformin in differential diagnoses.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Headache is among the most frequently encountered symptoms in clinical practice.
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Key Findings & Data:In this report, we present a 54-year-old female patient who developed occipital neuralgia-like symptoms shortly after the initiation of metformin treatment for type 2 diabetes mellitus.
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Conclusion & Impact:It underscores the importance of considering uncommon side effects of commonly prescribed medications, such as metformin in differential diagnoses.
🔬Design:Olgu Sunumu
📍Scope:Comprehensive Sample
⚙️Variables:Oksipital nevralji · Metformin · Baş ağrısı

Abstract

Headache is among the most frequently encountered symptoms in clinical practice. Occipital neuralgia is characterized by sudden, sharp, electric shock-like pains in the distribution area of the occipital nerve. In this report, we present a 54-year-old female patient who developed occipital neuralgia-like symptoms shortly after the initiation of metformin treatment for type 2 diabetes mellitus. The symptoms resolved following the discontinuation of the drug. This case is discussed in light of the literature to highlight a potentially rare headache pattern triggered by metformin. This case describes an unusual form of headache possibly associated with metformin therapy. It underscores the importance of considering uncommon side effects of commonly prescribed medications, such as metformin in differential diagnoses.

Özet

Baş ağrısı, klinik pratikte en sık karşılaşılan semptomlardan biridir. Oksipital nevralji, özellikle oksipital sinirin innervasyon alanında ani, keskin, elektrik çarpması tarzında ağrılarla karakterizedir. Bu çalışmada, tip 2 diabetes mellitus tanısıyla başlanan metformin tedavisinden kısa süre sonra gelişen ve ilacın kesilmesiyle gerileyen, oksipital nevralji benzeri semptomlar gösteren 54 yaşındaki kadın hasta sunulmuştur. Bu olgu, metformin ile tetiklenmiş olabilecek nadir bir baş ağrısı paternini vurgulamak amacıyla literatür ışığında tartışılmıştır. Bu olgu, metformin tedavisi ile ilişkili nadir bir baş ağrısı formunu tanımlamaktadır. Metformin gibi sık kullanılan ilaçların, alışılmadık yan etkilerle ilişkili olabileceği akılda tutulmalı ve ayırıcı tanıda bu tür ilişkiler göz önünde bulundurulmalıdır.

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Cite This Article

Kaygisiz, S., Gul, T. (2025). Sleep-Related Headache Following Metformin Use: Hypnic or Toxic?. ODÜ Tıp Dergisi, Cilt: 12 Sayı: 1, 14–18. https://doi.org/10.56941/odutip.1663213

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