Journals / Celal Bayar Üniversitesi Fen Bilimleri Dergisi / 2018 / Cilt: 14 - Sayı: 3

Characterization of Carotid Atherosclerotic Plaques by Measurement of Acoustic Impedance

Pages
321–325
Publication Date
2018-09-30
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Lipid pool, together with fibrous tissue and calcified regions are the indications of vulnerable plaques, therefore, the determination of these regions within the plaques by SAM will help to evaluate the risk of thrombosis or stenosis and effect the decision making of the operations of the patients.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:In this study, acoustic properties of carotid atherosclerotic plaques are studied ex vivo by scanning acoustic microscope (SAM).
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Key Findings & Data:An 80 MHz transducer was used in SAM, during the observation of the plaques.
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Conclusion & Impact:Lipid pool, together with fibrous tissue and calcified regions are the indications of vulnerable plaques, therefore, the determination of these regions within the plaques by SAM will help to evaluate the risk of thrombosis or stenosis and effect the decision making of the operations of the patients.
🔬Design:Lab & Field Experiment
📍Scope:Comprehensive Sample
⚙️Variables:Scanning acoustic microscopy · carotid artery · atherosclerosis

Abstract

In this study, acoustic properties of carotid atherosclerotic plaques are studied ex vivo by scanning acoustic microscope (SAM). Human carotid atherosclerotic plaques were collected from patients by carotid erdarterectomy operation technique. An 80 MHz transducer was used in SAM, during the observation of the plaques. For the fibrous tissue, acoustic impedance was measured as 2.02 ± 0.06 MRayl, while for the lipid pool it was measured as 1.70 ± 0.07 MRayl and for the calcified region within the intima it was measured as 2.23 ± 0.09 MRayl. The difference in acoustic impedance values is due to the variation of elasticity within the atherosclerotic plaques. Lipid pool, together with fibrous tissue and calcified regions are the indications of vulnerable plaques, therefore, the determination of these regions within the plaques by SAM will help to evaluate the risk of thrombosis or stenosis and effect the decision making of the operations of the patients.

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Cite This Article

BİLEN, B., KAFA, Ü., ÜNLÜ, M. B. (2018). Characterization of Carotid Atherosclerotic Plaques by Measurement of Acoustic Impedance. Celal Bayar Üniversitesi Fen Bilimleri Dergisi, Cilt: 14 - Sayı: 3, 321–325. https://ajindex.com/articles/107075

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References (14)

  1. Bentzon, JF, Otsuka, F, Virmani, R, Falk, E, Mechanism of Plaque formation and Rupture, Circulation Research, 2014, 114, 1852-1866
  2. Insull, W, The Pathology of Atherosclerosis: Plaque Development and Plaque Responses to Medical Treatment, The American Journal of Medicine, 2009, 122(1A), S3-14
  3. Puri, R, Worthley, MI, Nicholls, SJ, Intravascular imaging of vulnerable coronary plaque: current and future concepts, Nature Reviews Cardiology, 2011, 8, 131-139
  4. Carlier, SG, Tanaka, K, Studying Coronary Plaque Regression with IVUS: A Critical Review of Recent Studies, Journal of Interventional Cardiology, 2016, 19(1), 11-15
  5. Li, J, Chen, Z, Integrated intravascular ultrasound and optical coherence tomography technology: a promising tool to identify vulnerable plaques, Journal of Biomedical Photonics and Engineering, 2016, 1(4), 209-224
  6. Jansen, K, Van Soest, G, Van Der Steen, AF, Intravascular photoacoustic imaging: a new tool for vulnerable plaque identification, Ultrasound in Medicine and Biology, 2014, 40(6), 1037-1048
  7. Wang, B, Su, JL, Karpiouk, AB, Intravascular Photoacoustic Imaging, IEEE Journal of Selected Topics in Quantum Electronics, 2010, 16(3), 599-599
  8. Yeager, D, Karpiouk, A, Wang, B, Amirian, J, Sokolov, K, Smalling, R, Emelianov, S, Intravascular photoacoustic imaging of exogenously labeled atherosclerotic plaque through luminal blood, Journal of Biomedical Optics, 2012, 17(10), 106016
  9. Berer, T, Grun, H, Bauer-Marschallinger, J, Burgholzer, P, Passler, K, Nuster, R, Paltauf, G. In IEEE International Ultrasonics Symposium, Dresden, Germany, 2012, 10.1109/ULTSYM.2012.0356
  10. Kobayashi, K, Yoshida, S, Saijo, Y, Hozumi, N, Acoustic impedance microscopy for biological tissue characterization, Ultrasonics, 2014, 54, 1922–1928
  11. Hozumi, N, Nakano, A, Terauchi, S, Nagao, M, Yoshida, S, Kobayashi, K, Yamamoto, S, Saijo, Y. In IEEE International Ultrasonics Symposium, New York, NY, USA, 2007, 1051-0117/07
  12. De Korte, DL, Pasterkamp, G, Van Der Steen, AFW, Woutman, HA, Bom, N, Characterization of Plaque Components with Intravascular Ultrasound Elastography in Human Femoral and Coronory Arteries In Vitro, Circulation, 2000, 102(6), 617-623
  13. Virmani, R, Kolodgie, FD, Burke, AP, Farb A, Schwartz, SM, Lessons from sudden coronary death: a comprehensive morphological classification scheme for atherosclerotic lesions, Arteriosclerosis, Thrombosis, and Vascular Biology, 2000, 20, 1262-1275
  14. Bailey, G, Meadows, J, Morrison,