Journals / Harran Üniversitesi Tıp Fakültesi Dergisi / 2015 / Cilt: 12 - Sayı: 2

Primary plasma cell leukemia: evaluation of a rare disease

Primer Plazma Hücreli Lösemi: Nadir Bir Hastalığın Değerlendirilmesi

Pages
300–302
Publication Date
2015-08-30
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

The aim of this report is to draw attention to PCL.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Plasma cell leukemia (PCL) is a rare and aggressive cancer involving plasma cells.
📊
Key Findings & Data:There are two forms of PCL (with or without multiple myeloma).
💡
Conclusion & Impact:The aim of this report is to draw attention to PCL.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Plazma hücresi · primer plazma hücreli lösemi · multiple myeloma diskoid

Abstract

Plasma cell leukemia (PCL) is a rare and aggressive cancer involving plasma cells. There are two forms of PCL (with or without multiple myeloma). Although patients with primary and secondary PCL share several clinical features, important differences exist. We report on a case diagnosed with primary PCL. We analyzed the clinicopathologic and laboratory features of the disease. The aim of this report is to draw attention to PCL.

Özet

Plazma hücreli lösemi (PHL), plazma hücrelerini içeren agresif ve nadir görülen bir kanserdir. PHL, multle myelomanın birlikte olduğu ve olmadığı şekilde iki formu (primer, seconder) bulunmaktadır. Primer ve seconder PHL'li olguların birçok klinik özellikleri benzer olsada önemli farklılıklar bulunmaktadır. Bu olgu sunumunda primer PHL'li bir hastanın klinik, patolojik ve laboratuar bulguları incelenmiştir. Bu olgu sunumunun amacı PHL'e dikkat çekmektir.

🔖

Cite This Article

SARIGUZEL, F. M., AYGUN, B., KARAKUKCU, Ç., ARSAV, V., KOCER, D., GODEKMERDAN, A. (2015). Primary plasma cell leukemia: evaluation of a rare disease. Harran Üniversitesi Tıp Fakültesi Dergisi, Cilt: 12 - Sayı: 2, 300–302. https://ajindex.com/articles/106896

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (10)

  1. Dimopoulos MA, Palumbo A, Delasalle KB, Alexanian R. Primary plasma cell leukemia. Br J Haematol 1994; 44: 754-9
  2. Kyle RA, Maldonado JE, Bayrd ED. Plasma cell leukemia. Report on 17 cases. Arch Intern Med 1974; 133: 813-8
  3. Garcia-Sanz R, Orfao A, Gonzalez M, Tabernero MD, Blade J, Moro MJ et al. Primary plasma cell leukemia: Clinical, immunophenotypic, DNA ploidy, and cytogenetic characteristics. Blood 1999; 93: 1032-37
  4. Candoni A, Tiribelli M, Fanin R. Plasma cell leukemia occuring in a patient with thrombocythemia treated with hydroxyurea and busulphan. Leuk Lymph 2004; 45: 821- 824
  5. Jain D, Singh T, Akhila L, Ghosh N. Primary plasma cell leukemia in a 30-year-old woman. Indian J Pathol Microbiol 2008; 51: 456-7
  6. Van de Donk NWCJ, Lokhorst HM, Anderson KC, Richardson PG. How I treat plasma cell leukemia. Blood 2012; 120: 2376-89
  7. Van Camp B, Durie BGM, Spier C, De Waele M, Van Riet I, Vela E et al. Plasma cells in multiple myeloma Express a natural killer cell-associated antigen: CD56 (NKH-1, Leu-19). Blood 1990; 76:377
  8. San Miguel JF, Gonzalez M, Gascon A, Moro MJ, Hernandez JM, Ortega F et al. Immunophenotype heterogeneity of multiple myeloma: Influence on the biology and clinical course of the disease. Br J Haematol 1991; 77: 185
  9. Tembhare PR, Subramanian PG, Sehgal K, Yajamanam B, Kumar A, Gadge V et al. Immunophenotypic profile of plasma cell leukemia: a retrospective study in a reference cancer center in India and rewiew of literature. Indian J Pathol Microbiol 2011; 54: 294-8
  10. Goyal M, Mohammad N, Palanki SD, Vaniawala SN. Primary plasma cell leukemia with light chain secretion and multiple chromosomal abnormalities: how successfully treated? Acase report with rewiev of literature. Indian J Med Paediatr Oncol 2010; 31: 96-100.