Journals / Bağımlılık Dergisi / 2020 / Cilt: 21 - Sayı: 2

HCV Infection and Treatment Rates in Opioid Dependent Patients Hospitalized in an Alcohol and Drug Addiction Treatment Center Clinic

Bir AMATEM Kliniğinde Yatan Opioid Bağımlısı Hastalarda HCV Enfeksiyonu ve Tedavi Oranları

Pages
108–114
Publication Date
2020-06-30
DOI
—
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AI Summary & Key Takeaways

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⚡ TL;DR(Too Long; Didn't Read)

It was found that 6.9% (n=2) of the anti HCV positive patients continued their regular outpatient controls after discharge, while anti HCV negative patients came to regular controls at a statistically significant rate with 25.1% (n=59).

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: The aim of this study was to investigate the factors related with anti HCV positivity rates and post discharge hepatitis C infection follow-up and treatment rates of the patients who was diagnosed with opioid use disorder.Method: The data of this study was collected by retrospective examination of the records of 265 patients aged 18 and over who were diagnosed with opioid use disorder according to DSM-5 diagnostic criteria and received inpatient treatment in an Alcohol and Drug Addiction Treatment Center (ADATC) clinic between 2017 and 2018.Results: Anti HCV was positive in all male gender and 10.9% (n=29) patients.
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Key Findings & Data:It was found that 6.9% (n=2) of the anti HCV positive patients continued their regular outpatient controls after discharge, while anti HCV negative patients came to regular controls at a statistically significant rate with 25.1% (n=59).
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Conclusion & Impact:New strategies should be developed to struggle HCV infection in addicted patients in order to direct the patients to treatment, to stay in treatment and to ensure their regular follow-up.
🔬Design:Research Article
📍Scope:2017 Verileri
⚙️Variables:addiction · infection · hepatitis c

Abstract

Objective: The aim of this study was to investigate the factors related with anti HCV positivity rates and post discharge hepatitis C infection follow-up and treatment rates of the patients who was diagnosed with opioid use disorder.Method: The data of this study was collected by retrospective examination of the records of 265 patients aged 18 and over who were diagnosed with opioid use disorder according to DSM-5 diagnostic criteria and received inpatient treatment in an Alcohol and Drug Addiction Treatment Center (ADATC) clinic between 2017 and 2018.Results: Anti HCV was positive in all male gender and 10.9% (n=29) patients. It was found that 6.9% (n=2) of the anti HCV positive patients continued their regular outpatient controls after discharge, while anti HCV negative patients came to regular controls at a statistically significant rate with 25.1% (n=59). As a result of the orientation after discharge, 31% of anti HCV positive patients applied to the department of infectious diseases, and 44.4% (n=4) of applicants received direct antiviral therapy.Conclusion: Treatment compliance of the patients with anti HCV positivity was insufficient in terms of both opioid use and hepatitis C infection. New strategies should be developed to struggle HCV infection in addicted patients in order to direct the patients to treatment, to stay in treatment and to ensure their regular follow-up.

Özet

Amaç: Bu çalışmada, opioid kullanım bozukluğu tanılı yatan hastaların anti HCV pozitiflik oranları ve taburculuk sonrası hepatit C enfeksiyonu takip ve tedavi oranları ile ilişkili faktörlerin incelenmesi amaçlanmıştır.Yöntem: Çalışmanın verileri; 2017 ve 2018 yılları arasında bir Alkol Madde Bağımlılığı Araştırma Tedavi ve Eğitim Merkezi’nde (AMATEM) yatarak tedavi gören, 18 yaş ve üzeri, DSM-5 tanı ölçütlerine göre opioid kullanım bozukluğu tanılı 265 hastanın kayıtlarının geriye dönük incelenmesi ile toplandı.Bulgular: Anti HCV, tamamı erkek, %10,9 (n=29) hastada pozitif saptandı. Anti HCV pozitif hastaların %6,9’unun (n=2) taburculuk sonrası düzenli AMATEM poliklinik kontrollerine devam ettiği, negatif hastaların ise %25,1 (n=59) ile istatistiksel olarak anlamlı olacak şekilde daha yüksek oranda düzenli kontrollere geldiği saptandı (p<0.00). Taburculuk sonrası yapılan yönlendirme sonucunda anti HCV pozitif hastaların %31’inin (n=9) enfeksiyon hastalıkları başvurusu olduğu, başvuranların ise %44,4’ünün (n=4) direk etkili antiviral tedavi aldığı tespit edildi.Sonuç: Anti HCV pozitif saptanan hastaların hem opioid kullanımı hem de hepatit C enfeksiyonu açısından tedavi uyumlarının yetersiz olduğu saptandı. Bağımlı hastalarda HCV enfeksiyonu ile mücadelede hastaların tedaviye yönlendirilmesi, tedavide kalmaları ve düzenli takiplerinin sağlanması amacıyla yeni stratejilerin geliştirilmesi önerilir.

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Cite This Article

UĞURLU, T. T., GÜVENDİK, C., ATEŞÇİ, F. (2020). HCV Infection and Treatment Rates in Opioid Dependent Patients Hospitalized in an Alcohol and Drug Addiction Treatment Center Clinic. Bağımlılık Dergisi, Cilt: 21 - Sayı: 2, 108–114. https://ajindex.com/articles/106595

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References (16)

  1. Sezak N, Tosun S, Eriş N, Ayer A. Ruh sağlığı hastanesinde yatarak tedavi gören hastalarda hepatit B ve hepatit C infeksiyonlarının sıklığı ve buna etkili faktörlerin değerlendirilmesi. Klimik Derg 2011; 24: 154-157
  2. Yetim A, Sahin M. İntravenöz madde bağımlısı gençlerde hepatit C virusu (HCV) infeksiyonu: sosyodemografik değerlendirme ve HCV genotip analizi. Klimik Derg 2018; 31: 190–194
  3. Davis SM, Daily S, Kristjansson AL, et al. Needle exchange programs for the prevention of hepatitis C virus infection in people who inject drugs: A systematic review with meta-analysis. Harm Reduct J 2017; 14: 1–15
  4. Evren C, Bilici R, Ucbilek E, Inan D. A call to action for the prevention of hepatitis C infection among intravenous drug users in Turkey. Dusunen Adam 2017; 30: 271–277
  5. Anagnostou O, Fotiou A, Kanavou E, et al. Factors associated with HCV test uptake in heroin users entering substitution treatment in Greece. HIV Medicine 2018; 19: 34–39
  6. Kulaksızoğlu B, Kara H, Özçelik Ö, Kuloğlu M. Opioid bağımlılığının tedavisinde naltrekson implant kullanımı: Geriye dönük bir çalışma. Anadolu Psikiyatri Derg 2019; 20: 133-138
  7. Mırsal H, Kalyoncu ÖA, Pektaş Ö, et al. Damar yolundan eroin kullananlarda hepatit B, hepatit C ve HIV yaygınlığı. Bağımlılık Dergisi 2003; 4: 10–14
  8. Altuğlu İ, Tanyeri S, Zeytinoğlu A, Altıntoprak AE. Madde kullanımı olan olgularda HBsAg, Anti-HCV ve Anti-HIV seroprevalansı: Retrospektif bir değerlendirme. Noropsikiyatri Ars 2019; 56: 186-190
  9. Cummins CA, Erlyana E, Fisher DG, Reynolds GL. Hepatitis C infection among Hispanics in California. J Addict Dis. 2015; 34: 263–273
  10. Lewer D, Tweed EJ, Aldridge RW, Morley KI. Causes of hospital admission and mortality among 6683 people who use heroin: A cohort study comparing relative and absolute risks. Drug Alcohol Depend 2019; 204: 1-5
  11. Wang X, Zhang T, Ho WZ. Opioids and HIV/HCV infection. J Neuroimmune Pharmacol 2011; 6: 477–489
  12. Lee J, Conniff J, Kraus C, Schrager S. A brief clinical update on hepatitis C. WMJ 2015; 114: 263–270
  13. Amerikan Psikiyatri Birliği. Ruhsal Bozuklukların Tanısal ve Sayımsal El Kitabı (DSM-5), Köroğlu E (Çeviri editör)
  14. Baskı, Ankara: Hekimler Yayın Birliği, 2013
  15. Su S, Mao L, Zhao J, et al. Epidemics of HIV, HCV and syphilis infection among synthetic drugs only users, heroin-only users and poly-drug users in Southwest China. Sci Rep 2018; 8: 1–10
  16. Berbesi-Fernández DY, Segura-Cardona AM, Montoya-Velez LP, Santamaría AÁ. Use