Journals / Bağımlılık Dergisi / 2019 / Cilt: 20 - Sayı: 4

Complete Blood Count Parameters and Lymphocyte-Related Ratios in Patients with Alcohol Use Disorder

Alkol Kullanım Bozukluğu Olan Hastalarda Tam Kan Sayımı Parametreleri ve Lenfositle İlişkili Oranlar

Pages
206–213
Publication Date
2019-12-29
DOI
—
🏛️Bibliographic metadata and full text access for this article are provided via DergiPark.
DergiPark Record ↗
✨

AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Conclusion: CBC can be used as a rapid and inexpensive examination in AUD patients with heavy alcohol consumption to obtain information about inflammatory processes. and immunological systems which may be useful in AUD diagnosis treatment and follow-up.

📌 3 Key Takeaways

🎯
Objective & Hypothesis:Objective: The study aimed to determine complete blood count (CBC) parameters, lymphocyte-related ratios in alcohol use disorder (AUD) patients with heavy alcohol use.Method: The dependent group included 75 individuals with history of alcohol use for at least 10 years.
📊
Key Findings & Data:The control group included 75 healthy individuals.Results: Alcohol use was 6.04 ± 1.45 units/day and the mean duration of alcohol use was 27.62 ± 8.68 years.
💡
Conclusion & Impact:Conclusion: CBC can be used as a rapid and inexpensive examination in AUD patients with heavy alcohol consumption to obtain information about inflammatory processes. and immunological systems which may be useful in AUD diagnosis treatment and follow-up.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Alcoholism · blood cell count

Abstract

Objective: The study aimed to determine complete blood count (CBC) parameters, lymphocyte-related ratios in alcohol use disorder (AUD) patients with heavy alcohol use.Method: The dependent group included 75 individuals with history of alcohol use for at least 10 years. CBC parameters were obtained by evaluating the required tests before alcohol detoxification was initiated. The control group included 75 healthy individuals.Results: Alcohol use was 6.04 ± 1.45 units/day and the mean duration of alcohol use was 27.62 ± 8.68 years. There were significant differences between the groups based on white blood cell (WBC), neutrophil count, percentage, monocyte count, percentage, neutrophil to lymphocyte ratio (NLR), monocyte to lymphocyte ratio (MLR), favoring the dependent group. There were significant differences between the groups based on lymphocyte percentage, eosinophil count, percentage, basophil percentage, RBC and eosinophil to lymphocyte ratio (ELR), favoring the control group. Conclusion: CBC can be used as a rapid and inexpensive examination in AUD patients with heavy alcohol consumption to obtain information about inflammatory processes. and immunological systems which may be useful in AUD diagnosis treatment and follow-up.

Özet

Amaç: Ağır alkol tüketimi olan alkol kullanım bozukluğu (AKB) hastalarında tam kan sayımı (CBC) parametreleri ve lenfosit-ilişkili oranların araştırılması planlandı.Yöntem: En az 10 yıldır alkol kullanımı olan 75 kişiden ‘bağımlı grup’ oluşturuldu. CBC parametreleri, alkol detoksifikasyonuna başlanmadan önce istenen tetkiklerin değerlendirilmesiyle elde edildi. 75 sağlıklı kişiden ‘kontrol grubu’ oluşturuldu. Bulgular: Alkol kullanım miktarı 6.04±1.45 birim/gün, alkol kullanım süresi ortalama 27.62±8.68 yıl idi. Beyaz küre (WBC), nötrofil sayısı, yüzdesi, monosit sayısı, yüzdesi, nötrofil-lenfosit oranı (NLO), monosit-lenfosit oranı (MLO) bağımlı grubunda daha yüksek olmak üzere, gruplar arasında anlamlı farklılık vardı. Lenfosit yüzdesi, eozinofil sayısı, yüzdesi, bazofil yüzdesi, RBC, eozinofil-lenfosit oranı (ELO) kontrol grubunda daha yüksek olmak üzere gruplar arasında anlamlı farklılık vardı. Sonuç: CBC, kısa sürede yapılan ucuz bir tetkik olarak, ağır alkol tüketen AKB tanılı hastalarda teşhis koymada ve takipte enflamatuvar süreçler ve immünolojik sistem hakkında bilgi veren yöntem olarak kullanılabilir.

🔖

Cite This Article

BAYKARA, S., KAYA, Ş., BERK, Ş. Ş. (2019). Complete Blood Count Parameters and Lymphocyte-Related Ratios in Patients with Alcohol Use Disorder. Bağımlılık Dergisi, Cilt: 20 - Sayı: 4, 206–213. https://ajindex.com/articles/106587

📄 Full Text PDF Viewer

📄

PDF görüntüleyici hazırlanıyor...

References (17)

  1. Referans 1 Schuckit MA. Alcohol-use disorders. Lancet 2009
  2. Referans 2 Camarini R, Pautassi RM, Mendez M, et al. Behavioral and neurochemical studies in distinct animal models of ethanol's motivational effects. Curr Drug Abuse Rev 2010
  3. Referans 3 Bouchery EE, Harwood HJ, Sacks JJ, et al. Economic costs of excessive alcohol consumption in the US, 2006. Am J Prev Med 2011
  4. Referans 4 Guzel D, Yazici AB, Yazici E, et al. Alterations of the hematologic cells in synthetic cannabinoid users. J Clin Lab Anal 2017
  5. Referans 5 Mert DG, Terzi H. Mean platelet volume in bipolar disorder: the search for an ideal biomarker. Neuropsychiatr Dis Treat 2016
  6. Referans 6 Özdin S, Sarisoy G, Böke Ö. A comparison of the neutrophil-lymphocyte, platelet-lymphocyte and monocyte-lymphocyte ratios in schizophrenia and bipolar disorder patients–a retrospective file review. Nord J Psychiatry 2017
  7. Referans 7 Liu L, Chen M, Zhao L, et al. Ethanol Induces Platelet Apoptosis. Alcohol Clin Exp Res 2017
  8. Referans 8 Szabo G, Catalano D, White B, et al. Acute alcohol consumption inhibits accessory cell function of monocytes and dendritic cells. Alcohol Clin Exp Res 2004
  9. Referans 9 Whelan G. Alcohol-related health problems in the elderly. Med J Aust 1995
  10. Referans 10 Orum MH, Kara MZ, Egilmez OB. Relationship between immune cells and alcohol dependents and controls: what about the lymphocyte-related ratios? J Immunoassay Immunochem 2018
  11. Referans 11 Association AP. Diagnostic and statistical manual of mental disorders (DSM-5®): American Psychiatric Pub
  12. Referans 12 Riis P. Perspectives on the Fifth Revision of the Declaration of Helsinki. Jama 2000
  13. Referans 13 Parry H, Cohen S, Schlarb JE, et al. Smoking, alcohol consumption, and leukocyte counts. Am J Clin Pathol 1997
  14. Referans 14 Nogueira LC, do Rio RF, Lollo PCB, et al. Moderate Alcoholic Beer Consumption: The Effects on the Lipid Profile and Insulin Sensitivity of Adult Men. J Food Sc 2017
  15. Referans 15 Nelson S, Kolls JK. Alcohol, host defence and society. Nat Rev Immunol 2002
  16. Referans 16 Zhang P, Bagby GJ, Stoltz DA, et al. Granulocyte colony-stimulating factor modulates the pulmonary host response to endotoxin in the absence and presence of acute ethanol intoxication. J Infect Dis 1999
  17. Referans 17 Szabo I, Rojavin M, Bussiere JL, et al. Suppr