Journals / Türk Pediatri Arşivi / 1999 / Cilt: 34 Sayı: 2

Intralesional Corticosteroid Injections with Short Term Oral Prednisolone For Treatment of Complicated Hemangiomas of the Skin in Infants

Süt Çocuklarının Komplike Cilt Hemanjiomlarının Tedavisinde Lezyon İçi Kortikosteroid ve Kısa Dönem Oral Prednizolon Uygulaması

Pages
1–1
Publication Date
1999-06-01
DOI
—
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⚡ TL;DR(Too Long; Didn't Read)

Although various methods of treatment are described for complicated hemangiomas the treatment modalities of these are still controversial Between 1993 and 1997 fifteen infants with complicated cutaneous hemangiomas have prospectively been treated by intralesional corticosteroid injections triamcinolone dexamethasone and short term oral prednisolon therapy The localizations of the hemangiomas were as follows: eyelid 3 upperlimb 2 retroauricular 2 labium major 3 forehead 1 lower limb 1 submandible 1 neck 1 and forearm 1 The indications for treatment were; ulceration 2 bleeding 2 infection 3 ambliopy 3 unesthetic apperance 2 and both infection and bleeding 3 The moan age of the patients was 7 4 3 2 months 2 5 12 months and all of them were female No visceral hemangioma and platelet trapping were determined in any case An average of 2 9±1 2 intralesional injections were performed Mean regression obtained was 75 8±19 4 13 patients The remaining two hemangiomas were unchanged The patients did not present with early or late complications in their follow up period with an avarage duration of 27 months As a result intralesional corticosteroid injections with short term oral prednisolone treatment are effective modes of therapy for complicated cutaneous hemangiomas in infants Key words: Cutaneous Hemangioma Corticosteroid Infant

📌 3 Key Takeaways

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Objective & Hypothesis:Although various methods of treatment are described for complicated hemangiomas the treatment modalities of these are still controversial Between 1993 and 1997 fifteen infants with complicated cutaneous hemangiomas have prospectively been treated by intralesional corticosteroid injections triamcinolone dexamethasone and short term oral prednisolon therapy The localizations of the hemangiomas were as follows: eyelid 3 upperlimb 2 retroauricular 2 labium major 3 forehead 1 lower limb 1 submandible 1 neck 1 and forearm 1 The indications for treatment were; ulceration 2 bleeding 2 infection 3 ambliopy 3 unesthetic apperance 2 and both infection and bleeding 3 The moan age of the patients was 7 4 3 2 months 2 5 12 months and all of them were female No visceral hemangioma and platelet trapping were determined in any case An average of 2 9±1 2 intralesional injections were performed Mean regression obtained was 75 8±19 4 13 patients The remaining two hemangiomas were unchanged The patients did not present with early or late complications in their follow up period with an avarage duration of 27 months As a result intralesional corticosteroid injections with short term oral prednisolone treatment are effective modes of therapy for complicated cutaneous hemangiomas in infants Key words: Cutaneous Hemangioma Corticosteroid Infant
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Key Findings & Data:Although various methods of treatment are described for complicated hemangiomas the treatment modalities of these are still controversial Between 1993 and 1997 fifteen infants with complicated cutaneous hemangiomas have prospectively been treated by intralesional corticosteroid injections triamcinolone dexamethasone and short term oral prednisolon therapy The localizations of the hemangiomas were as follows: eyelid 3 upperlimb 2 retroauricular 2 labium major 3 forehead 1 lower limb 1 submandible 1 neck 1 and forearm 1 The indications for treatment were; ulceration 2 bleeding 2 infection 3 ambliopy 3 unesthetic apperance 2 and both infection and bleeding 3 The moan age of the patients was 7 4 3 2 months 2 5 12 months and all of them were female No visceral hemangioma and platelet trapping were determined in any case An average of 2 9±1 2 intralesional injections were performed Mean regression obtained was 75 8±19 4 13 patients The remaining two hemangiomas were unchanged The patients did not present with early or late complications in their follow up period with an avarage duration of 27 months As a result intralesional corticosteroid injections with short term oral prednisolone treatment are effective modes of therapy for complicated cutaneous hemangiomas in infants Key words: Cutaneous Hemangioma Corticosteroid Infant
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Conclusion & Impact:Although various methods of treatment are described for complicated hemangiomas the treatment modalities of these are still controversial Between 1993 and 1997 fifteen infants with complicated cutaneous hemangiomas have prospectively been treated by intralesional corticosteroid injections triamcinolone dexamethasone and short term oral prednisolon therapy The localizations of the hemangiomas were as follows: eyelid 3 upperlimb 2 retroauricular 2 labium major 3 forehead 1 lower limb 1 submandible 1 neck 1 and forearm 1 The indications for treatment were; ulceration 2 bleeding 2 infection 3 ambliopy 3 unesthetic apperance 2 and both infection and bleeding 3 The moan age of the patients was 7 4 3 2 months 2 5 12 months and all of them were female No visceral hemangioma and platelet trapping were determined in any case An average of 2 9±1 2 intralesional injections were performed Mean regression obtained was 75 8±19 4 13 patients The remaining two hemangiomas were unchanged The patients did not present with early or late complications in their follow up period with an avarage duration of 27 months As a result intralesional corticosteroid injections with short term oral prednisolone treatment are effective modes of therapy for complicated cutaneous hemangiomas in infants Key words: Cutaneous Hemangioma Corticosteroid Infant
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Domain Parameters

Abstract

Although various methods of treatment are described for complicated hemangiomas the treatment modalities of these are still controversial Between 1993 and 1997 fifteen infants with complicated cutaneous hemangiomas have prospectively been treated by intralesional corticosteroid injections triamcinolone dexamethasone and short term oral prednisolon therapy The localizations of the hemangiomas were as follows: eyelid 3 upperlimb 2 retroauricular 2 labium major 3 forehead 1 lower limb 1 submandible 1 neck 1 and forearm 1 The indications for treatment were; ulceration 2 bleeding 2 infection 3 ambliopy 3 unesthetic apperance 2 and both infection and bleeding 3 The moan age of the patients was 7 4 3 2 months 2 5 12 months and all of them were female No visceral hemangioma and platelet trapping were determined in any case An average of 2 9±1 2 intralesional injections were performed Mean regression obtained was 75 8±19 4 13 patients The remaining two hemangiomas were unchanged The patients did not present with early or late complications in their follow up period with an avarage duration of 27 months As a result intralesional corticosteroid injections with short term oral prednisolone treatment are effective modes of therapy for complicated cutaneous hemangiomas in infants Key words: Cutaneous Hemangioma Corticosteroid Infant

Özet

Komplike hemanjiomların tedavisinde birçok tedavi metodu tanımlanmasına rağmen tedavi seçenekleri konusundaki tartışmalar devam etmektedir 1993 1997 yılları arasında komplike cilt hemanjiomlarının tedavisinde lezyon içi steroid triamsinolon deksametazon ve kısa süreli oral prednizolon uygulanan 15 süt çocuğu prospektif olarak incelenmiştir Hemanjiomların 3 ü göz kapağında 2 si üst dudakta 2 si kulak arkasında 3 ü labium majusta diğer olgularda ise alın alt dudak çene altı boyun ve ön kolda yerleşmişti Serideki olguların tedaviye alınma nedenleri; ülserasyon 2 kanama 2 enfeksiyon 3 ambliyopi 3 estetik olmayan görünüm 2 enfeksiyon ve kanama 3 idi Olguların yaş ortalaması 7 4±3 2 ay 2 5 12 ay olup tüm olgular kızdı Hiç bir olguda iç organ hemanjiomu ve trombositopeni saptanmadı Ortalama 2 9±1 2 kez lezyon içi steroid enjeksiyonu yapıldı 13 olgunun hemanjiomlarında ortalama 75 8±19 4 küçülme sağlandı Diğer 2 olguda ise hemanjiom boyutlarında değişme olmadı Ortalama 27 aylık takip süresince hiç bir olguda erken ve geç tedavi komplikasyonuna rastlanmadı Sonuç olarak süt çocuklarının komplike cilt hemanjiomlarının tedavisinde lezyon içi steroid enjeksiyonu ile beraber kısa dönem oral prednizolon uygulanması etkin bir tedavi yöntemidir Anahtar kelimeler: Cilt Hemanjiomu Kortikosteroid Süt Çocuğu

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Cite This Article

KIRIŞTIOĞLU, İ., KILIÇ, N., TÜRKEL, T., GÜRPINAR, A. N., DOĞRUYOL, H. (1999). Intralesional Corticosteroid Injections with Short Term Oral Prednisolone For Treatment of Complicated Hemangiomas of the Skin in Infants. Türk Pediatri Arşivi, Cilt: 34 Sayı: 2, 1–1. https://ajindex.com/articles/1012257

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