Journals / Turgut Özal Tıp Merkezi Dergisi / 2000 / Cilt: 7 Sayı: 2

Seropositivity of hepatitis B and hepatitis C viruses in blood and blood products in transfused and non-transfused patients with hematological malignancies

KAN VE KAN ÜRÜNLERİ TRANSFÜZYONU YAPILAN VE YAPILMAYAN HEMATOLOJİK MALİGNİTELİ HASTALARDA HEPATİT B VE HEPATİT C VİRÜS SEROPOZİTİFLİĞİ

Pages
1–1
Publication Date
2000-04-01
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Key words: Hepatitis, transfusion, hematological malignancies.

📌 3 Key Takeaways

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Objective & Hypothesis:Objective: We investigated the seropositivity difference of hepatitis B and hepatitis C viruses in hematologically malignant patients with history of blood and blood products transfusions.
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Key Findings & Data:Material and methods: HBs Ag, Anti-HBs and anti-HCV antibody positivity were investigated in 35 hematologically malignant patients with history of transfusions and 52 patients without history of transfusions with ELISA in the department of Hematology.
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Conclusion & Impact:Key words: Hepatitis, transfusion, hematological malignancies.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:Hepatit · transfüzyon · hematolojik malignite

Abstract

Objective: We investigated the seropositivity difference of hepatitis B and hepatitis C viruses in hematologically malignant patients with history of blood and blood products transfusions. Material and methods: HBs Ag, Anti-HBs and anti-HCV antibody positivity were investigated in 35 hematologically malignant patients with history of transfusions and 52 patients without history of transfusions with ELISA in the department of Hematology. Results: Anti-HCV positivity was detected in 2.8% (n= 1) and 1.9% of patients (n= 1) with and without blood transfusion history, respectively. HBs Ag positivity was detected to be 22.8% (n= 8) in blood transfused group, and 5.7% (n= 3) in non-transfused group and 9% (n= 9) in the control group. Anti-HBs antibody positivity was detected in 31.4% of patients (n= 11) with a history of blood transfusion, 38.4% in the non-transfused group (n= 20), and 40% in the control group (n= 43). Conclusions: HBs Ag positivity was found to be significantly higher in the transfused group when compared with the non-transfused group and the control group (p<0.05). Key words: Hepatitis, transfusion, hematological malignancies.

Özet

Amaç: Kan ve kan ürünleri transfüzyonu öyküsü olan ve olmayan hematolojik maligniteli hastalarda, hepatitB ve hepatit C virüs seropozitifliği arasındaki fark araştınldı. Materyal ve metot: Hematoloji servisinde tedavi edilen, kan transfüzyon öyküsü olan 35 ve transfüzyon öyküsü olmayan 52 hematolojik maligniteli hastada HBs Ag, anti-HBs ve anti-HCV antikor pozitifliği EUSA yöntemi He araştınldı. Bulgular: Çalışmamızda hematolojik malign hastalığı olup transfüzyon yapılmış ve transfüzyon öyküsü olmayan gruplarda birer hastada anti-HCV seropozitifliği saptandı (%2.8, %1.9). HBs Ag seropozitifliği transfüzyon yapılan hasta grubunda %22.8 (n=8), transfüzyon yapılmayan hasta grubunda %5.7 (n=3), kontrol grubunda ise %9 (n=9) olarak bulunmuştur. Anti-HBs antikor seropozitifliği transfüzyon yapılan hasta grubunda %31.4 (n=ll), transfüzyon yapılmayan hasta grubunda %38.4 (n=20), kontrol grubunda %40 (n=43) oranında saptanmıştır. Sonuç: Kan transfüzyonu yapılmış olan hematolojik maligniteli hastalarda HBs Ag seropozitifliği, kan transfüzyonu yapılmamış hasta ve kontrol grubundan daha yüksek bulundu (p<0.05). Anahtar kelimeler: Hepatit, transfüzyon, hematolojik malignite

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Cite This Article

SARI, R., ÖZKAN, H. İ., SEVİNÇ, A., AYDOGDU, İ. (2000). Seropositivity of hepatitis B and hepatitis C viruses in blood and blood products in transfused and non-transfused patients with hematological malignancies. Turgut Özal Tıp Merkezi Dergisi, Cilt: 7 Sayı: 2, 1–1. https://ajindex.com/articles/1010468

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