Journals / Turgut Özal Tıp Merkezi Dergisi / 2011 / Cilt: 18 Sayı: 4

The Youngest Advanced Stage Grade III Endometrial Carcinoma: A Case Report

En Genç İleri Evre Grade III Endometrium Karsinomu: Olgu Sunumu

Pages
269–271
Publication Date
2011-08-01
DOI
—
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AI Summary & Key Takeaways

AI Insight
⚡ TL;DR(Too Long; Didn't Read)

Key words: Advanced Stage Endometrium Cancer; Youngest.

📌 3 Key Takeaways

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Objective & Hypothesis:Inroduction: Endometrail cancer, typically diagnosed in the postmenopausal years, is the most common gynecologic malignancy.
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Key Findings & Data:Case Report: A 23 year old female applied to the hospital because of postabortal bleeding despite revision curettage.
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Conclusion & Impact:Key words: Advanced Stage Endometrium Cancer; Youngest.
🔬Design:Research Article
📍Scope:Comprehensive Sample
⚙️Variables:İleri Evre Endometrium Kanseri · En Genç. · Advanced Stage Endometrium Cancer

Abstract

Inroduction: Endometrail cancer, typically diagnosed in the postmenopausal years, is the most common gynecologic malignancy. Young women with endometrial carcinoma are considered to have a favorable prognosis with early stage, well differentiated lesions. In this report we present young patient with advanced stage endometrial adenocarcinoma who had poor prognosis. Case Report: A 23 year old female applied to the hospital because of postabortal bleeding despite revision curettage. Endometral sampling was perfomed and grade 3 endometrail adenocarcinoma was diagnosed. Athought total abdominal hysterectomy, bilateral salphingoopherectomy, pelvic-paraaortic lymphadenectomy, infracolic omentectomy and chemotherapy were performed, recurrence of the tumor was observed one year after the surgery. The patient died because of sepsis in 24 years old. Conclusion: In this report endometrial cancer was observed in 23 years old patient with no obvious risk factor. This report is the youngest advanced stage grade 3 endometrial adenocarcinoma in the literature. Further studies to evaluate the etyopathogenic mechanisms of endometrial cancer without risk factors are needed. Key words: Advanced Stage Endometrium Cancer; Youngest.

Özet

Giriş: Sıklıkla posmenapozal dönemde izlenen endometrium karsinomu en sık görülen jinekolojik malignensidir. Literatürde genç endometrial karsinom vakalarının; polikistik over hastalığı zemininde gelişen diferansiye erken evre kanserler olduğu vurgulanmaktadır. Bu makalede genç yaşta izlenen, ileri evre, kötü prognozlu endometrium karsinomu vakası sunulmuştur. Olgu Sunumu: Abortus sonrası revizyon küretaj yapılmasına rağmen vajinal kanaması devam eden 23 yaşındaki hastaya endometrial biopsi uygulanmış, patolojik inceleme sonucu Grade 3 adenokarsinom olarak gelmiştir. Yapılan operasyonda 8000 cc asit mai boşaltılmış, total abdominal histerektomi, bilateral salfingooferektomi, parsiyel omentektomi, bilateral pelvik-paraaortik lenf nodu diseksiyonu uygulanmıştır. Altı kür taksol-karboplatin kemoterapisi alan hastada operasyondan yaklaşık bir yıl sonra nüks gelişmiş, verilen kemoterapiye yanıt alınamamıştır. Hasta sepsis sebebiyle 24 yaşında kaybedilmiştir. Sonuç: Bu makalede endometriun kanseri, hiçbir risk faktörü saptanmayan 23 yaşındaki hastada izlenmiştir. Bu hasta literatürde bizim saptadığımız en genç ileri evre grade 3 endometrium kanseri olgusudur. Risk faktörleri dışında endometrium kanseri etyopatogenezinde rol alan mekanizmaları ortaya koyacak yeni yayınlara ihtiyaç vardır. Anahtar kelimeler: İleri Evre Endometrium Kanseri; En Genç.

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Cite This Article

Öztürk, E., Uğur, M. G., Özkan, Y., Aydın, A., Balat, Ö. (2011). The Youngest Advanced Stage Grade III Endometrial Carcinoma: A Case Report. Turgut Özal Tıp Merkezi Dergisi, Cilt: 18 Sayı: 4, 269–271. https://ajindex.com/articles/1009895

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