Dergiler / Acta Veterinaria Eurasia / 2017 / Cilt: 43 Sayı: 1
Histopathological and immunohistochemical characteristics of ventricular ependymoma in a goat
- Sayfa
- 77–80
- DOI
- —
Özet
Ependymomas as primary central nervous system neoplasms are occasionally observed in human infants however; they are rare in animals. A three-year-old male goat was presented with clinical neurological signs. At necropsy, a 3×2×2 cm, bulging, white-grey- to red, soft mass extending into the left lateral ventricle of brain was observed. Microscopically, the mass with densely cellular population was nonencapsulated, mostly containing cuboidal-columnar neoplastic cells with pseudo-rosettes formation. Mitotic figures were rare and malignancy indexes were not observed. Neoplastic cells were immunohistochemically positive for Glial Fibrillary Acidic Protein (GFAP), S-100, and vimentin; however, they did not express Cytokeratins. On the basis of the location, histologic and immunohistochemical findings, the tumor was diagnosed as an ependymoma.
Abstract
Ependymomas as primary central nervous system neoplasms are occasionally observed in human infants however; they are rare in animals. A three-year-old male goat was presented with clinical neurological signs. At necropsy, a 3×2×2 cm, bulging, white-grey- to red, soft mass extending into the left lateral ventricle of brain was observed. Microscopically, the mass with densely cellular population was nonencapsulated, mostly containing cuboidal-columnar neoplastic cells with pseudo-rosettes formation. Mitotic figures were rare and malignancy indexes were not observed. Neoplastic cells were immunohistochemically positive for Glial Fibrillary Acidic Protein (GFAP), S-100, and vimentin; however, they did not express Cytokeratins. On the basis of the location, histologic and immunohistochemical findings, the tumor was diagnosed as an ependymoma.