Approach to the metastatic bone lesions; tumor investigation in a patient without cancer

Abstract

With the increase in the use of radiological imaging methods, the number of patients with a bone lesion (mostly in the form of a lytic lesion) or metastasis suspicion is also increasing. Patients with such a suspicious bone lesion are referred to internal medicine outpatient clinics for further investigation. However, there is no a standard approach for tumor investigation in incidental bone lesions in the literature. In this article, we mentioned about definition, clinical findings and diagnostic approach to these lesions.