Dergiler / New Trends in Medicine Sciences / 2020 / Cilt: 1 - Sayı: 1

Role of Hyperoside on Ovarian Tissue Damage Created by Ovarian Torsion Detorsion

Role of Hyperoside on Ovarian Tissue Damage Created by Ovarian Torsion Detorsion

Mustafa Can GÜLER, Ayhan TANYELİ

Sayfa
1–5
DOI
—

Abstract

Purpose: Here, hyperoside (HYP) was investigated against ovarian tissue injury induced by bilateral ovarian torsion detorsion (T/D) model. Material and Methods: 18 Sprague Dawley female rats were grouped as sham, torsion detorsion (T/D) and T/D+HYP. Sham group, abdominal incision was performed and repaired with no additional intervention. T/D group, T/D model was established. T/D+HYP group, HYP was administered by oral gavage prior to detorsion. Following detorsion, rats were sacrificed and the ovarian tissues were excised. Results and Conclusion: Oxidant parameters declined and antioxidant values elevated in T/D group compared to sham group. HYP treatment decreased oxidant biomarkers and increased antioxidant mediators. After all, HYP prevented ovarian tissue injury generated by T/D model in rats.