Is mean platelet volume better than other long-used non-invasive parameters in assessing severe fibrosis in patients with chronic hepatitis B?

Abstract

Background & Aims: This study was aimed to investigating the correlation between the severity of hepatic fibrosis and mean platelet volume (MPV) and comparing the accuracy rate of MPV with that of other long-used non-invasive parameters in predicting severe hepatic fibrosis in patients with chronic hepatitis B (CHB). Materials and Methods: Ninety-nine patients with CHB were enrolled. The patients were assigned to two groups, based on their hepatic fibrosis scores. Those with scores ranging from 0 to 3 (mild to moderate fibrosis) were assigned to Group 1, and those with scores ranging from 4 to 6 (severe fibrosis) were included in Group 2. Results: The mean age of the patients was 4213, and 69 (70%) of them were male. Twenty two patients (22%) were in Group 2. Patients in Group 2 displayed significantly lower albumin and platelet count (p