Sinus node dysfunction associated with hypothyroidism

Abstract

Sinus node dysfunction (SND) is defined as any disturbance or abnormality of the function of the sinus node and is rare in children. In order to assess the association of SND and thyroid disease, we have prospectively evaluated cardiac status of patients with hypo and hyperthyroidism presenting to our department of pediatrics in a year. Among the T 35 hypothyroidic patients, a 12 year old girl who complained of fatigue and dizziness; a routine electrocardiogram (ECO suggested sinus node dysfunction with severe bradycardia, sinus arrythmia, sinus pause and junctional rhythm periods. The diagnosis was confirmed by Holier monitoring and exercise test. Thyroid hormone replacement therapy was started. However two months later permenant pacemaker was implanted for persisting clinical and ECC findings. This patient represent an example for the rare association of SND with thyroid disfunction children and indicates, this arrythmia is not always reversible with appropriate therapy of thyroid disease.