Hepatitis B seroprevalence in hematological oncology patients

Abstract

Objectives: Hepatitis B virus (HBV) infection is still a serious public health problem today. Many factorssuch as frequent blood transfusion, hemodialysis, sexual contact, sterilization in surgical procedures, etc. areinvolved in the transmission of hepatitis B virus. In our study, HBV seroprevalence was evaluatedretrospectively in order to provide vaccination of anti-HBs negative patients and to determine HBV prophylaxisin patients with hematological malignancy.Methods: A total of 499 patients were included in the study. HBsAg, anti-HBs, anti-HBc IgG, anti-HDV, HBVDNA values were measured by ELISA (enzyme-linked immunosorbent assay, Liason, Diasorin, Italy) withReal-Time PCR (Cobas-Tagman, Roche Switzerland) and recorded. The obtained datas were evaluated bySPSS for Windows 15.00 statistical program. A value of p