Akut Romatizmal Karditli Çocukların Elektrokardiyografilerinde Kardiyak Elektrofizyolojik Denge İndeksi

Index of Cardiac Electrophysiological Balance in Electrocardiography of Children with Acute Rheumatic Carditis

Özet

Amaç: Çalışmamızda akut romatizmal karditli çocukların elektrokardiyografilerinde kardiyak elektrofizyolojik denge indeksi (iCEB), ve kardiyak aritmi için diğer risk belirteçlerinin incelenmesi amaçlanmıştır. Hastalar ve Yöntem: Ocak 2016-Ağustos 2018 tarihleri arasında, akut romatizmal kardit tanılı 40 çocuk hasta ile yaş ve cinsiyet olarak benzer 40 sağlıklı çocuk retrospektif olarak çalışmaya alındı. Tüm vakaların demografik özellikleri kayıtlardan elde edildi. Elektrokardiyografide; P dalga dispersiyonu (Pd), QT dispersiyonu (QTd) ve düzeltimiş QTd (QTcd) süreleri, Tp-e intervali (Tp-e), Tp-e/QT ve Tp-e/QTc oranları, ve iCEB ve düzeltilmiş iCEB (iCEBc) ölçüm değerleri gruplar arasında karşılaştırıldı. İstatistiksel olarak p

Abstract

Aim: In this study, examination of the index of cardiac-electrophysiological balance (iCEB) and of other risk markers for cardiac arrhythmia in electrocardiography of children with acute rheumatic carditis was aimed. Patients and Methods: Forty pediatric patients with acute rheumatic carditis and 40 healthy children matched in terms of gender and age were retrospectively enrolled in the study between January 2016 and August 2018. Demographic data of all cases were obtained from records. By electrocardiography, P dispersion (Pd), dispersion durations of QT (QTd) and corrected QT (QTcd), Tpeak-to-end interval (Tpe), ratios of Tp-e/QT and Tp-e/QTc, and measurements of iCEB and corrected iCEB (iCEBc) were all compared between the groups. Statistically significant dif ference was accepted as p< 0.05. Results: In the patient and control groups, mean ages were 11.40±3.48 years and 11.41±3.31 years, respectively. Both groups had 16 female (40%) and 24 male (60%) children. In the patient group, heart rate, PR interval, Pd, QTd, QTcd, Tp-e, Tp-e/QT ratio and iCEBc were found to be significantly increased. Though iCEB level was higher in the patient group, there was no statistically significant difference with healthy controls. Conclusion: In children with acute rheumatic carditis, repolarization-depolarization balance may be impaired. Therefore, in addition to other electrocardiographic risk parameters for arrhythmia, use of iCEB(c) may also be beneficial. However , further studies on this issue are needed.