Dergiler / Records of Natural Products / 2022 / Cilt: 16 - Sayı: 5

A New Eremophilanolide from the Fresh Roots of Rehmannia glutinosa

A New Eremophilanolide from the Fresh Roots of Rehmannia glutinosa

Yangang CAO, Yingjie REN, Yanling LIU, Mengnan ZENG, Mengna WANG, Chen XU, Xiling FAN, He CHEN, Xiaoke ZHENG, Weisheng FENG

Sayfa
509–514
DOI
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Abstract

A new eremophilanolide, serratifolide F (1), and six known compounds were isolated from the fresh roots of Rehmannia glutinosa. Their structures were characterized by analysis of NMR, CD, HRESIMS, and comparison of the data in previous literatures. The protective effects against lipopolysaccharide (LPS)-stimulated damage on normal rat kidney tubule epithelioid (NRK-52e) cells of the compounds were evaluated using MTT assay and real time cellular analysis