Dergiler / Records of Natural Products / 2022 / Cilt: 16 - Sayı: 3

Two New 13-oxomilbemycins from a NTG-Induced Mutation Strain of Streptomyces avermitilis AVE-H39

Two New 13-oxomilbemycins from a NTG-Induced Mutation Strain of Streptomyces avermitilis AVE-H39

Ji-Dong WANG, Bing LI, Wen-Sheng XIANG, Shao-Yong ZHANG, Yi WU, Li-Quin ZHANG, Huan QI

Sayfa
206–211
DOI
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Abstract

Two new 13-oxomilbemycins, 13-oxomilbemycin β3 (1) and 25-ethyl-13-oxomilbemycin β3 (2), were isolated from the broth of a NTG-induced mutation strain of Streptomyces avermitilis AVE-H39. The structures of 1 and 2 were determined based on MS and extensive NMR analysis. Compounds 1 and 2 possessed moderate nematocidal activity.