Dergiler / Records of Natural Products / 2022 / Cilt: 16 - Sayı: 5

A New Alkaloid from the Endophytic Fungus of Crocus sativus L., Aspergillus fumigatus Y0107

A New Alkaloid from the Endophytic Fungus of Crocus sativus L., Aspergillus fumigatus Y0107

Yu JIANG, Chunxiao JIANG, Qi ZHOU, Ping WANG, Yingpeng TONG

Sayfa
463–470
DOI
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Abstract

A new alkaloid (compound 1), together with 8 known alkaloids (compounds 2-9), were isolated from Aspergillus fumigatus Y0107 extracts from the lateral buds of Crocus sativus Linn (saffron). The structure of compound 1 was elucidated with NMR spectroscopy, High-resolution electrospray ionization mass spectrometry (HR-ESI-MS) and compared with its analogues in the literatures. The antibacterial activities of the crude ethyl acetate (EA) extract (CEE) and isolated compounds (compounds 1, 2, 6, 8) were evaluated against plant pathogenic bacteria. Compound 2 and the CEE demonstrated moderate inhibitory activity with MICs of 100 μg/mL against Erwinia sp.