Umbilikal kord ve yenidoğan sonuçları arasındaki ilişki

İsmail BIYIK, Cenk SOYSAL, Nadi KESKİN, Özlem ERTEN, Halil İbrahim ŞİŞMAN, Burak DELİLOĞLU, Damla Geçkalan SOYSAL

Özet

Amaç: Çal›flmam›zda, düflük riskli gebeliklerde (gestasyonel yafla gö- re normal fetüsler [AGA]) umbilikal ven çap› ile kordon uzunlu¤u ve fetal sonuç aras›ndaki iliflkiyi araflt›rd›k. Yöntem: Gebeli¤in 38+0 ve 41+6. haftalar› aras›nda 19–44 yafl›n- daki 39 tekil gebelikten oluflan prospektif bir kohort çal›flmas› ger- çeklefltirildi. Olgular›n demografik özellikleri, prenatal ultrason ile ölçülen umbilikal ven çap›, postnatal do¤um a¤›rl›¤›, cinsiyet, 1. ve 5. dakika Apgar skorlar›, kan gaz› analizi ve umbilikal kord uzun- lu¤u kaydedildi. Gestasyonel haftaya göre 10–90. persantilde olan fetal a¤›rl›kl› fetüsler AGA kabul edildi. Bulgular: Gebelerin ortalama yafl› 27.5±5.3 idi. Gebelerin %33’ü (13/39) nullipard›. Korelasyon analizinde umbilikal ven çap› ve di- ¤er de¤iflkenler aras›nda istatistiksel olarak anlaml› korelasyon yoktu (p>0.050). Umbilikal kord uzunlu¤u ve umbilikal ven laktat seviyesinin istatistiksel olarak negatif ve anlaml› korelasyona sahip oldu¤u bulundu (r=-0.418; p=0.015); ancak di¤er gebelik sonuçla- r›nda anlaml› korelasyon yoktu. Cinsiyete göre umbilikal ven çap› ve kordon uzunlu¤unun medyan de¤erleri aras›nda istatistiksel olarak anlaml› fark yoktu (s›ras›yla p=0.076 ve 0.181). Sonuç: Sonuç olarak çal›flmam›zda, 38.0–41.6 haftal›k gebelikler- de (AGA fetüslerde) umbilikal ven çap› ve kordon uzunlu¤u ile fe- tal a¤›rl›k ve gebelik sonucu aras›nda bir iliflki bulamad›k. Ancak elde edilen sonuçlar›n yine de daha büyük seriler ile do¤rulanma- s› gerekmektedir.

Abstract

Objective: This study investigated the relationship between umbil- ical vein diameter and cord length and fetal outcome in low-risk pregnancies (fetuses appropriate for gestational age [AGA]). Methods: A prospective cohort study of 39 singleton pregnant women aged 19–44 years at between 38+0 and 41+6 weeks of gesta- tion was conducted. Case demographics, umbilical vein diameter measured by prenatal ultrasound, postnatal birth weight, gender, 1- and 5-minute Apgar scores, blood gas analysis, and umbilical cord length were recorded. Fetuses with a fetal weight in the 10–90th per- centile according to week of gestation were accepted as AGA. Results: The mean age of the pregnant women was 27.5±5.3 years. 33% (13/39) of the pregnant women were nulliparous. There was no statistically significant correlation between umbilical vein diameter and other variables in correlation analysis (p>0.050). Umbilical cord length and umbilical vein lactate level were found to have a statistical- ly negative and significant correlation (r=-0.418; p=0.015); however, no other pregnancy outcomes were found to have a significant corre- lation. There was no statistically significant difference between the median values of umbilical vein diameter and cord length by gender (p=0.076 and 0.181, respectively). Conclusion: In conclusion, this study found no relationship between umbilical vein diameter and cord length and fetal weight and pregnancy outcome in low-risk 38.0–41.6-week pregnancies (AGA fetuses). However, the obtained results still need to be con- firmed by larger series.