Obstruktif Uyku Apnesi olan kişilerde tam kan parametrelerinin CPAP tedavisi ile ilişkisi

Response of Blood Parameters to CPAP Treatment in Patients with Obstructive Sleep Apnea

Özet

Introduction: Many studies have evaluated the relationship between the NLR and PLR in patients with obstructive sleep apnea (OSA), and have shown that they are related to inflammation. We evaluated whether 3 months of continuous positive airway pressure (CPAP) treatment in patients with moderate to severe OSA without any comorbidities would affect the NLR and PLR values. Methods: Full blood count parameters were evaluated before and after 3 months of CPAP treatment in patients with a diagnosis of moderate to severe OSA without any comorbidities. Results: Twenty-nine patients (18 [62.1%] males) were enrolled. The mean body mass index (BMI) was 34.85±5.75 kg/m2, the apneahypopnea index score was 49.85±27.42, and CPAP was 9.34±1.77. No significant change in BMI was observed after the third month of treatment. Although the Epworth Sleepiness Scale (ESS) score decreased significantly (p=0.000), no changes were observed in the NLR, PLR, or C-reactive protein level (p>0.05). Mean platelet volume and red blood cell distribution width changed significantly after treatment (p=0.01; p

Abstract

Introduction: Many studies have evaluated the relationship between theNLR and PLR in patients with obstructive sleep apnea (OSA), and haveshown that they are related to inflammation. We evaluated whether 3months of continuous positive airway pressure (CPAP) treatment inpatients with moderate to severe OSA without any comorbidities wouldaffect the NLR and PLR values.Methods: Full blood count parameters were evaluated before and after3 months of CPAP treatment in patients with a diagnosis of moderate tosevere OSA without any comorbidities.Results: Twenty-nine patients (18 [62.1%] males) were enrolled. Themean body mass index (BMI) was 34.85±5.75 kg/m2, the apneahypopnea index score was 49.85±27.42, and CPAP was 9.34±1.77.No significant change in BMI was observed after the third month oftreatment. Although the Epworth Sleepiness Scale (ESS) score decreasedsignificantly (p=0.000), no changes were observed in the NLR, PLR, orC-reactive protein level (p>0.05). Mean platelet volume and red bloodcell distribution width changed significantly after treatment (p=0.01;p