Signet ring cell carcinoma of the breast (Case report)

Abstract

In this article an unusual case of signet ring cell carcinoma (SRC Ca) of mammary is reported. The diagnosis was established using a mastectomy specimen from a 70-years old woman who was initially examined for left quadrant mass and left nipple discharge. Many breast carcinomas irrespective of histologic type, do contain SRC's in small numbers (I). But they were never as frequent as in the case we reported (1). A confused entity signet ring cell (SRC) Ca of the breast have been seperated recently as an aggressive subtype of breast cancer, distinct from mucinous (colloid) carcinomas (2,3,4). The distinctive clinical and pathologic features of SRC ca and because of their vastly different prognoses (2,3,4), warrant seperation of this group of tumors from .other forms of breast ca.