A patient with systemic sclerosis with advances cardiac and skeletal muscle involvement ( A case report )

Abstract

This report describes a patient with progressive systemic sclerosis with polymyositis who had myocardial infarction. Myocardial involvement in systemic sclerosis is due to two reasons: Noninflammatory and inflammatory involvement. The former group is due to noninflammatory intramyocardial vasospasm similar to peripheral vasospasm, and the later is from inflammatory myocarditis, that associated with peripheral "inflammatory myositis". It is important to differentiate these two subgroups, because the inflammatory'myositis, like their polimyositis-dermatomyositis counterparts, has an excellent response to anti-inflammatory therapy. Myocarditis rarely been reported in some patients with systemic sclerosis in association with myositis. So we reported this case as an cardiac and skeletal muscle disease in systemic sclerosis.