Dergiler / Journal of Ankara Medical School / 2001 / Cilt: 23 - Sayı: 2
Plasma insulin and C-peptide levels in non-diabetic essential hypertensive patients
- Sayfa
- 123–128
- DOI
- —
Özet
Amaç: Diyebetes mellitusu ve glükoz intoleransı olmayan esansiyel hipertansif hastalardaki hiperinsülinemiyi ve bunun obezite ve lipid metabolizma bozukluklarıyla olan ilişkisini araştırmayı amaçladık. Hastalar ve yöntem: Elli esansiyel hipertansif hasta ve 19 normotensif hasta çalışmaya dahil edildi. Plazma insulin, C-peptid, üre, kreatinin, ürik asit, aspartat aminotransferaz, alanın aminotransferaz, gama-glutamil transpeptidaz, düşük dansiteli lipoprotein kolestreol, çok düşük dansiteli lipoprotein kolesterol ve total yüksek dansiteli lipoprotein kolesterol düzeyleri ölçüldü. Bulgular: Plazma C-peptid düzeyleri hipertansif hastalarda istatiksel anlamlı olarak yüksek bulunurken (p
Abstract
Objective: We aimed to investigate the presence of hyperinsulinemia and its relation to obesity and other lipid metabolism disorders in essential hypertensive patients who have no diabetes mellitus or glucose intolerance. Design and methods: This study comprised 50 essential hypertensive and 19 normotensive patients. All patients had oral glucose tolerance tests. Plasma insulin, C-peptide, urea, creatinin, uric acid, aspartate aminotransferase, alanine aminotransferase, gamma-glutamyl transpeptidase, very low density lipoprotein cholesterol, low density lipoprotein cholesterol and total high density lipoprotein cholesterol levels were measured. Results: Plasma C-peptide levels were found to be significantly higher in hypertensive patients (p