Correlation between dental caries and hormonal, biochemical parameters in children with early childhood caries

Abstract

Aim: The aim of this study was to analyze the correlation between dentalcaries and hormonal, biochemical parameters in pediatric patients withearly childhood caries (ECC).Methodology: This study was conducted on fifty pediatric patients whopresented with complaints of pain and caries and underwent dentaltreatment under general anaesthesia. In this study, the hormonal,biochemical parameters (glucose, urea, uric acid, creatinine, AST, ALT,GGT, CRP, Sodium, Potassium, Calcium, Glucose, Iron, TSH, FT3 and FT4)which were routinely taken from patients before general anaesthesia andthe number of decayed, extracted and filled teeth (dmft) obtained as aresult of clinical and radiographic examination were evaluatedstatistically in patients aged 2-6 years. Statistical analysis was performedusing Mann Whitney U Test and Spearman correlation coefficient at a0.05% significance level.Results: According to the data obtained, the mean dmft of fifty children(male: 35; female: 15) included in the study was found to be 8.66±3.17.The mean dmft was 7.93±3.06 in females and 8.97±3.21 in males. Nostatistical difference was found between dmft and gender in statisticalanalysis. (p>0.05). Uric acid and GGT values, which are among thehormonal and biochemical parameters, were found to be outside thenormal range in 61.22% of the patients. However, statistical analysisrevealed that there was no significant relationship between dmft andhormonal, biochemical parameters (p>0.05).Conclusion: In this study, it was concluded that dental caries did notcause a significant change in hormonal and biochemical blood parametersin pediatric patients with ECC.