Nanotechnology for preparation of array platforms

Abstract

The design and production of advanced array technologies, referred also as “biochips”, have attracted tremendous interest of the scientific community due to the broad application possibilities of these materials especially in the life sciences. It is especially useful in detection of multiple targets of biologic origin. Patterning of substrate surfaces is one of the major steps in the preparation of the arrays. Several techniques for the preparation of array platforms have been developed. Here, the basic information on nanotechnological approaches using atomic force microscope (AFM), i.e., dip-pen lithography, conducting AFM lithography, nanoshaving and nanografting, are briefly described.