Phenolics separation by molecularly imprinted monolithic CEC column

Abstract

Capillary electrochromatography (CEC) has investigated as a technique for the separation of the following phenolic compounds: phenol, o- and m-cresol, p-dichlorophenol and 2,6-dichlorophenol, p- and o-nitrophenol. We have proposed novel CEC monolithic column for selective separation of phenolics by Methacrylamidoantipyrine, MAAP, as a new charge-transfer monomer via multiple interactions (both hydrogen bonding and hydrophobic interactions) and 4-nitrophenol. We have combined molecular imprinting with the ability of methacryloyl based modification in CEC column between p-nitrophenol and MAAP to create CEC-monolith suitable for phenol, o- and m-cresol, pdichlorophenol and 2,6-dichlorophenol, p- and o-nitrophenol separation.