Effects of intraperitoneal anaesthesia on pain and endocrine response to gynaecologic laparoscopy

Abstract

The effects of'intraperitoneal administration of bupivacaine on pain and the endocrine response to gynaecologic laparoscopy were studied in 30 female patients. 20 ml bupivacaine 0.25 % admi¬nistered into peritoneal cavity and right subdiaphragmatic area 10 min before the procedure (n = 15). 0.9 % NaCl was administered to the control group of patients (n — 15). Analgesic requirement, pain scores and endocrine response were investigated. There were no significant differences in pain scores and pethidine requirements between the groups during the first 4 hours following laparoscopy but endocrine stress res¬ponse were less in bupivacaine administrated group than saline group during and after the procedure. Our results suggest that 20 ml bupivacaine 0.25 % intraperitoneally does not affect postoperative pain but it is efficient in reducing endocrine response to gynaecologic laparoscopy.