Dergiler / Damar Cerrahi Dergisi / 2013 / Cilt: 22 - Sayı: 1

Alt ekstremite derin ven trombozunda kateter aracılığıyla trombolizin erken dönem sonuçları

Catheter-Directed thrombolysis for lower extremity deep venous thrombosis; short term results of catheter-directed thrombolysis for deep vein thrombosis

Sayfa
124–129
DOI
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Özet

Objective: Thrombosis of the deep veins in the supragenicular region is a common clinical condition. Pharmacomechanical assisted removal of the thrombus for the initial management may provide the complete recovery with preservation of normal venous valve function.Material and Methods: Seventeen patients with deep vein thrombosis were treated using ultrasound- accelerated catheter-directed thrombolysis in addition to standard anticoagulant therapy. After 6 months, venous patency of the treated vessels was investigated using duplex ultrasound.Results: Thrombolysis was successful in 70.6% (12/17) of the patients. Twelve patients had complete clot lysis (>90% restored patency). Bleeding at the catheter-insertion site was observed infour patients. No pulmonary embolism was seen. In one patient, peroneal nerve injury occurred.Conclusion: Ultrasound-accelerated catheter-directed thrombolysis may be a promising treatment in patients with lower extremity deep vein thrombosis.

Abstract

Objective: Thrombosis of the deep veins in the supragenicular region is a common clinical condition. Pharmacomechanical assisted removal of the thrombus for the initial management may provide the complete recovery with preservation of normal venous valve function.Material and Methods: Seventeen patients with deep vein thrombosis were treated using ultrasound- accelerated catheter-directed thrombolysis in addition to standard anticoagulant therapy. After 6 months, venous patency of the treated vessels was investigated using duplex ultrasound.Results: Thrombolysis was successful in 70.6% (12/17) of the patients. Twelve patients had complete clot lysis (>90% restored patency). Bleeding at the catheter-insertion site was observed infour patients. No pulmonary embolism was seen. In one patient, peroneal nerve injury occurred.Conclusion: Ultrasound-accelerated catheter-directed thrombolysis may be a promising treatment in patients with lower extremity deep vein thrombosis.