Dergiler / Çocuk Sağlığı ve Hastalıkları Dergisi / 2001 / Cilt: 44 - Sayı: 2

Obez çocuklarda serum lipidleri ve lipid peroksidasyonunun araştırılması

Investigation of serum lipids and lipid peroxidation in obese children

Sayfa
135–140
DOI
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Özet

Serum lipidleri ve lipid peroksidasyonunun araştırılması amacıyla, 7-12 (9.51 $pm$ 1.12) yaşları arasında 43 sağlıklı normal çocuk ile yaşları 7-12 (9.98±1.39) arasında 33 obez çocuğun serumlarında trigliserid, total kolesterol, serbest kolesterol, LDL-kolesterol , HDL-kolesterol, HDL2-kolesterol, HDL3-kolesterol, lipoprotein(a) ve lipid peroksidasyonu düzeylerine bakıldı ve sırasıyla obezlerde 120.19±53.17 mg/dl, 172.53$pm$30.07 mg/dl, 41.30± 11.14 mg/dl, 103.51 ±28.09 mg/dl, 42.48±7.90 mg/dl, 8.04±4.75 mg/dl, 34.44+5.68 mg/ di, 19.44±16.91 mg/dl, 3.98±1.84 nmol/ml; kontrol grubunda 78.30±35.11 mg/dl, 151.42 $pm$ 23.84 mg/dl, 33.65±9.63 mg/dl, 88.82±22.22 mg/dl, 47.03±6.13 mg/dl, 14.75±5.62 mg/ml, 32.27+4.31 mg/ml, 10.45±8.43 mg/ dl, 3.26$pm$1.08 nmol/ml bulundu. Obezlerde trigliserid, total kolesterol, serbest kolesterol, LDL-kolesterol, lipoprotein(a), lipid peroksidasyonu değerlerinin (p

Abstract

This study was carried out on 43 healthy children aged between 7-12 years (9.5±1.1) and 33 obese children aged between 7-12 years (10.0+1.4) to investigate serum levels of triglyceride total cholesterol, free cholesterol, LDL-cholesterol, HDL-cholesterol, HDL2-cholesterol, HDL3-cholesterol, lipoprotein(a) and lipid peroxidation. Results in the obese group were 120.2±53.2 mg/dl, 172.5±30.1 mg/dl, 41.3±11.1 mg/dl, 103.5±28.1 mg/dl, 42.5±7.9 mg/dl, 8.0±4.8 mg/dl, 34.4±5.7 mg/dl, 19.4±16.9 mg/dl, and 4.0±1.8 nmol/ml and in the control group, were 78.3$pm$35.1 mg/dl, 151.4±23.8 mg/dl, 33.7±9.6 mg/dl, 88.8±22.2 mg/dl, 47.0±6.1 mg/dl, 14.8±5.6 mg/dl, 32.3±4.3 mg/dl, 10.5$pm$8.4 mg/dl, and 3.3 $pm$ 1.1 nmol/ml, respectively. Serum levels of triglyceride total cholesterol, free cholesterol, LDL-cholesterol, lipoprotein(a) and lipid peroxidation of the obese group were significantly increased, and of HDL-cholesterol and HDL2-cholesterol decreased (p