Factors in Relation with in-Hospital Mortality in Geriatric Patients with COVID-19

Abstract

BACKGROUND/AIMS: The World Health Organization has designated a severe acute respiratory syndrome as coronavirus-2 (SARS-CoV-2) infection. It is caused by a new coronavirus novel coronavirus disease-2019 (COVID-19), which was initially diagnosed in December, 2019 in Wuhan, China. SARS-CoV-2 infection particularly affects the geriatric age group, with a more severe progress rate of the disease. This study aimed to define the clinical characteristics of geriatric individuals with COVID-19 and investigate the in-hospital mortality rate and its predictors. MATERIALS AND METHODS: This was a descriptive and retrospective research. This research covered all individuals over the age of 60 who were admitted to hospital with a COVID-19 diagnosis. The demographics, physical examination findings, vital signs, hospital outcomes, comorbidities, and laboratory results of these patients were assessed. The main results were the discovery of the hospital mortality rate and its determinants. RESULTS: A total of 168 elderly individuals with positive polymerase chain reaction (PCR) test findings were included in this research. 51.8 percent of the patients were female, with a median age of 67 years. The patients in our research had an in-hospital death rate of 10.7%. We found that high troponin and fibrinogen and low oxygen saturation at the time of admission had a negative effect on survival. CONCLUSION: High troponin and fibrinogen levels, as well as low oxygen saturation levels at the time of admission, were found to be the most important predictors of in-hospital death in elderly COVID-19 patients according to our study results. We believe that it would be beneficial to monitor other parameters not only at the time of admission, but also during the hospitalization period of the patients.