Malign Safra Kesesi Polipleri için Risk Faktörleri

Özet

Amaç: Bu çalışmanın amacı safra kesesi poliplerinde malignite için risk faktörlerini belirlemektir.Yöntem: Safra kesesi polipi nedeniyle laparoskopik kolesistektomi uygulanan 92 hasta geriye dönük olarak incelendi. Hastaların demografik verileri, polip boyutu ve sayısı, safra taşı varlığı ve poliplerin histopatolojik özellikleri kaydedildi.Bulgular: 92 hasta dahil edildi. Ortalama yaş 45,78 ± 11,21 yıl (21-72) idi. Hastaların 59'u (64.1%) kadın, 33'ü (35.9%) erkekti. Ortalama polip boyutu 8.17 ± 2.19 mm ve 35 hastada (38.0%) tek polip varken 57 hastada (62.0%) çoklu polip (≥2) vardı. Hastaların 47'sinde (51.1%) safra taşı hastalığı varken 45'inde (48.9%) taş hastalığı yoktu. Benign polipler (Grup 1) 79 hastada (85,9%), adenokarsinomlar (Grup 2) 13 (14,1%) hastada saptandı. Benign poliplerin 71'i (77,1%) neoplastik olmayan polip ve 8'i (8,8%) neoplastik polip (adenom) idi. Adenokarsinomlu 13 hastanın 11'i (11.9%) T1a ve 2'si (2.2%) T1b idi. Grup 1'de ortalama yaş 44,32 ± 11,03, Grup 2'de 54,61 ± 8,07 yıldı ve Grup 2'de anlamlı olarak daha yaşlıydı (p = 0,002). Ortalama polip boyutu Grup 1'de 7,47 ± 5,51 mm, Grup 2'de 12,46 ± 1,89 mm idi ve anlamlı bir farkla (p

Abstract

Objective: The aim of this study is to determine risk factors for malignancy in gallbladder polyps.Method: 92 patients who underwent laparoscopic cholecystectomy due to gallbladder polyp were retrospectively analyzed. Demographic data of the patients, size and number of polyp, the presence of gallstones and histopathological features of the polyps were recorded.Results: 92 patients were included. Mean age was 45.78±11.21 years (21-72). 59 of the patients (64.1%) were female and 33 (35.9%) were male. Mean polyp size was 8.17±2.19 mm and 35 patients (38.0%) had a single polyp, while 57 (62.0%) had multiple polyps (≥2). 47 of the patients (51.1%) had gallstone disease, while 45 (48.9%) had no stone disease. Benign polyps (Group 1) were found in 79 patients (85.9%) and adenocarcinomas (Group 2) were found in 13 (14.1%). Of the benign polyps, 71 (77.1%) were non-neoplastic polyps and 8 (8.8%) were neoplastic polyps (adenomas). Of the 13 patients with adenocarcinomas, 11 (11.9%) were T1a and 2 (2.2%) were T1b. Mean age was 44.32±11.03 years in Group 1 and 54.61±8.07 years in Group 2, the latter being significantly older (p=0.002). Mean polyp size was 7.47±5.51 mm in Group 1 and 12.46±1.89 mm in Group 2, with a significant difference (p