Adneksiyal Kitlelerde, İntraoperatif Frozen Section İle Final Patoloji Arasındaki Uyumda Kappa Testinin Kullanımı

Concordance Between İntraoperative Frozen Section And Final Pathologyİn Adnexal Masses Using The Kappa Test

Özet

GİRİŞ ve AMAÇ: Adneksiyal kitlelerin teşhisi için intraoperatif frozen section (IFS) ile final histopatolojiksonuçlar arasındaki uyumu değerlendirmek. YÖNTEM ve GEREÇLER: Adneksiyal kitle nedeniyle IFS incelemesi yapılan 274 hastanın verileri retrospektifolarak toplandı. Adneksiyal kitlelerin teşhisinde IFS ve final histopatolojik sonuçlarının uyumu, rastgele uyumoranını düzelterek hesaplayan kappa testi kullanılarak değerlendirildi. BULGULAR: IFS ve final patoloji sonuçları arasındaki genel uyum oranı (%94,0), Cohen’s kappa tablosu iledeğerlendirildiğinde güçlü bir uyumu göstermiştir (K = 0,847; p

Abstract

INTRODUCTION: To evaluate the concordance between the intraoperative frozen section (IFS) and finalhistopathological results for diagnosing adnexal masses. METHODS: The data of 274 patients who underwent IFS examination of an adnexal mass were collectedretrospectively. The concordance of IFS and final histopathological results for diagnosing adnexal masses wasevaluated using the Kappa test, which was calculated by correcting the random fit rate. RESULTS: The overall agreement rate (94.0%) between the IFS and final pathology results showed strongagreement when evaluated with Cohen’s kappa table (K = 0.847; p < 0.001). The IFS sensitivity values were99.0%, 68.4%, and 84.0% for benign, borderline, and malignant cases, respectively. Specificity ratios were 84.1%,99.2%, and 98.7% for benign, borderline, and malignant cases, respectively. Prevalence rates were 74.8%, 6.9%,and 18.3% for benign, borderline, and malignant cases, respectively. DISCUSSION AND CONCLUSION: Strong concordance between IFS and final pathology results fordiagnosing adnexal masses showed that IFS is reliable even for borderline cases, which have the lowest prevalence.