Dergiler / Zeynep Kamil medical journal (Online) / 2021 / Cilt: 52 - Sayı: 3

Assessment of perinatal outcomes of pregnancies conceived by in vitro fertilization-intracytoplasmic sperm injection

Assessment of perinatal outcomes of pregnancies conceived by in vitro fertilization-intracytoplasmic sperm injection

Fırat TÜLEK, Bülent Berker, Alper KAHRAMAN

Sayfa
136–141
DOI
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Abstract

Objective: The objective of this study is to compare maternal and perinatal outcomes of singleton pregnancies obtained by in vitro fertilization/intracytoplasmic sperm injection (IVF/ICSI) treatment and spontaneously conceived singleton pregnancies. Material and Methods: Patient records of women conceived by IVF/ICSI and spontaneously conceived women that delivered in Ankara University, Department of Obstetrics and Gynecology after the 24th gestational week and whom the postnatal follow-ups of the infants were conducted in Ankara University, Department of Pediatrics, were retrospectively evaluated. Study group consists of 180 women with singleton IVF/ICSI pregnancies were. Control group included 624 spontaneously conceived women with singleton pregnancies that gave birth within the selected study period. Results: Median maternal age of the IVF/ICSI group was found significantly higher than the control group (p=0.031). A significantly higher incidence of hypertensive complications in pregnancy was found in IVF/ICSI group (p=0.001). Incidence of gestational diabetes mellitus was found significantly higher in IVF/ICSI group (p<0.001). Cesarean section rates were significantly higher in IVF/ICSI group in comparison with spontaneously conceived pregnancies (p<0.001). Preterm delivery rate is significantly higher in IVF/ICSI group (p<0.001). Infants born by IVF/ICSI pregnancies were showed a significantly higher rate of neonatal intensive care unit requirement in comparison with infants born by spontaneously conceived pregnancies (p<0.001). However, the statistical significance of the difference was observed to disappear after adjusting the data for gestational week at birth (p=0.161). Secondary sex ratio was found significantly lower in IVF/ICSI pregnancies (p=0.001). Conclusion: Singleton pregnancies conceived by IVF/ICSI present higher risk for some adverse perinatal outcomes and should be followed accordingly.